Cortical Activation to Auditory Mismatch Elicited by Frequency Deviant and Complex Novel Sounds: A PET Study

doi:10.1006/nimg.2002.1176

NeuroImage

Volume 17, Issue 1, September 2002, Pages 231-239

https://doi.org/10.1006/nimg.2002.1176 Get rights and content

Abstract

The analysis of auditory deviant events outside the focus of attention is a fundamental capacity of human information processing and has been studied in experiments on Mismatch Negativity (MMN) and the P3a component in evoked potential research. However, generators contributing to these components are still under discussion. Here we assessed cortical blood flow to auditory stimulation in three conditions. Six healthy subjects were presented with standard tones, frequency deviant tones (MMN condition), and complex novel sounds (Novelty condition), while attention was directed to a nondemanding visual task. Analysis of the MMN condition contrasted with the standard condition revealed blood flow changes in the left and right superior temporal gyrus, right superior temporal sulcus and left inferior frontal gyrus. Complex novel sounds contrasted with the standard condition activated the left superior temporal gyrus and the left inferior and middle frontal gyrus. A small subcortical activation emerged in the left parahippocampal gyrus and an extended activation was found covering the right superior temporal gyrus. Novel sounds activated the right inferior frontal gyrus when controlling for deviance probability. In contrast to previous studies our results indicate a left hemisphere contribution to a frontotemporal network of auditory deviance processing. Our results provide further evidence for a contribution of the frontal cortex to the processing of auditory deviance outside the focus of directed attention.

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Regular ArticleCortical Activation to Auditory Mismatch Elicited by Frequency Deviant and Complex Novel Sounds: A PET Study

Abstract

Biol. Psychiatry

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.

Neurophysiol. Clin.

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Clin. Neurophysiol.

Neuroimage

Neuroimage

NeuroImage

NeuroImage

Neuroimage

Biol. Psychol.

Biol. Psychiatry

Neurophysiol. Clin.

Neuroimage

Curr. Opin. Neurobiol.

NeuroImage

NeuroImage

Electroencephalogr. Clin. Neurophysiol.

Electroencephalogr. Clin. Neurophysiol.

NeuroImage

Rate-dependent activation of a prefrontal-insular-cerebellar network during passive listening to trains of click stimuli: An fMRI study

Neuroreport

“What” and “where” in the human auditory system

Proc. Natl. Acad. Sci. USA

Brain indices of automatic pattern processing

Neuroreport

Memory-related processing of complex sound patterns in human auditory cortex: A MEG study

Neuroreport

Processing of novel sounds and frequency changes in the human auditory cortex: Magnetoencephalographic recordings

Psychophysiology

Human temporal lobe activation by speech and nonspeech sounds

Cereb. Cortex

Modality-specific frontal and parietal areas for auditory and visual spatial localization in humans

Nature Neurosci.

Memory prerequisites of mismatch negativity in the auditory event-related potential (ERP)

J. Exp. Psychol. Learn. Mem. Cogn.

On the origin and development of the mismatch negativity

Ear Hear.

Disruption of attention to novel events after frontal lobe injury in humans

J. Neurol. Neurosurg. Psychiatry

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Brain

Dorsolateral prefrontal cortex activation during automatic auditory duration-mismatch processing in humans: A positron emission tomography study

Neurosci. Lett.

Attention dependent allocation of auditory processing resources as measured by mismatch negativity

Neuroreport

A cortical network sensitive to stimulus salience in a neutral behavioral context across multiple sensory modalities

J. Neurophysiol.

The parahippocampal region and auditory-mnemonic processing

Ann. N.Y. Acad. Sci.

Neural mechanisms of involuntary attention to acoustic novelty and change

J. Cogn. Neurosci.

Regular Article
Cortical Activation to Auditory Mismatch Elicited by Frequency Deviant and Complex Novel Sounds: A PET Study