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A Programmable Molecular Computer in Microreactors

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Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 3384))

Abstract

To solve problems with DNA in microreactors, static systems are not favourable due to programmability. It will be shown that solving Boolean logic with a programmable microfluidic system is a step forward in molecular computing. Not only the use of DNA as information carrier is important but also the integration of electronic computing to control the system and readouts. This paper will show that the optimal configuration of computing in microfluidics is a system containing components analogue with electronic elementary building blocks components, such as switches, logic gates and memory, making it programmable for any type of Boolean problem.

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References

  • van Noort, D., Austin, R.H.: Towards a bubbling brain in microfluidics. Manuscript in preparation

    Google Scholar 

  • Hirvensalo, M.: Quantum computing. Natural Computing Series. Springer, Berlin (2001)

    MATH  Google Scholar 

  • Adleman, L.M.: Molecular computation of solutions to combinatorial problems. Science 266, 1021–1024 (1994)

    Article  Google Scholar 

  • Amos, M., Owenson, G.G.: ERCIM News, vol. 43, pp. 36–37 (October 2000)

    Google Scholar 

  • Klein, J.P., Leete, T.H., Rubin, H.: A biomolecular implementation of logically reversible computation with minimal energy dissipation. BioSystems 52, 15–23 (1999)

    Article  Google Scholar 

  • Huang, Y., Duan, X., Cui, Y., Lauhon, L., Kim, K., Lieber, C.M.: Logic Gates and Computation from Assembled Nanowire Building Blocks. Science 294, 1313–1317 (2001)

    Article  Google Scholar 

  • Gehani, A., Reif, J.: Micro flow bio-molecular computation. BioSystems 52, 197–216 (1999)

    Article  Google Scholar 

  • McCaskill, J.S., Wagler, P.: From reconfigurability to evolution in construction systems: spanning the electronic, microfuidic and biomolecular domains. In: Grünbacher, H., Hartenstein, R.W. (eds.) FPL 2000. LNCS, vol. 1896, pp. 286–299. Springer, Heidelberg (2000)

    Chapter  Google Scholar 

  • McCaskill, J.S.: Optically programming DNA computing in microflow reactors. BioSystems 59, 125–138 (2001)

    Article  Google Scholar 

  • van Noort, D., Landweber, L.F.: Towards a re-programmable DNA computer. In: Chen, J., Reif, J.H. (eds.) DNA 2003. LNCS, vol. 2943. Springer, Heidelberg (2004)

    Chapter  Google Scholar 

  • van Noort, D., Gast, F.-U., McCaskill, J.S.: DNA computing in microreactors. In: Jonoska, N., Seeman, N.C. (eds.) DNA 2001. LNCS, vol. 2340, pp. 33–45. Springer, Heidelberg (2002)

    Chapter  Google Scholar 

  • Unger, M.A., Chou, H.-P., Thorsen, T., Scherer, A., Quake, S.R.: Monolithic Microfabricated Valves and Pumps by Multilayer Soft Lithography. Science 288, 113–116 (2000)

    Article  Google Scholar 

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© 2005 Springer-Verlag Berlin Heidelberg

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van Noort, D. (2005). A Programmable Molecular Computer in Microreactors. In: Ferretti, C., Mauri, G., Zandron, C. (eds) DNA Computing. DNA 2004. Lecture Notes in Computer Science, vol 3384. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11493785_32

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  • DOI: https://doi.org/10.1007/11493785_32

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-26174-2

  • Online ISBN: 978-3-540-31844-6

  • eBook Packages: Computer ScienceComputer Science (R0)

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