Abstract
Volumetric approaches for the analysis of hippocampal structures (HS) are required for the diagnosis of different diseases. In order to diagnose, evaluate and compare patient datasets, standardized and reproducible analysis supports physicians in clinical routine and research. In this paper, we present a practical application for volumetry in MR volume datasets. The approach combines the semiautomatic linear registration of an atlas based polygonal model with T1-weighted (based on inversion recovery protocol) and T2-weighted MR images and the automatic volumetric assessment of diseased structures. The approach was evaluated and compared with manually segmented MR datasets.
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References
Webb J, Guimond A, Eldridge P, Chadwick D, Meunier J, Thirion JP, et al. Automatic detection of hippocampal atrophy on magnetic resonance images. Magn Reson Imaging 2001;17(8):1149–1161.
Ashton EA, Parker KJ, Berg MJ, Chen C. Novel volumetrie feature extraction technique with applications to MR images. In: IEEE Trans Med Imaging. vol. 16(4); 1997. p. 365–371.
Lötjönen J, Mäkelä T. Elastic Matching Using a Deformation Sphere. In: Proc. of MICCAI; 2001. p. 541–548.
Shen D, Moffat S, Resnick SM, Davatzikos C. Measuring size and shape of the hippocampus in MR images using a deformable shape model. NeuroImage 2002;15(2):422–434.
wwwcerefycom. Cerefy Brain Atlas: Geometric Models 2.0; 2005.
Talairach J, Tournoux P. Co-Planar Stereotaxic Atlas of the human brain. Thieme Verlag; 1988.
Bazin PL, McAuliffe M, Gandler W, Pham DL. Free software tools for atlas-based volumetric neuroimage analysis. In: Proc. SPIE, Medical Imaging 2005: Image Processing. vol. 5747. San Diego; 2005. p. 1824–1833.
Alyassin AM, Lancaster JL, Downs JH, Fox PT. Evaluation of new algorithms for the interactive measurement of surface area and volume. Medical Physics 1994;21(6):741–52.
Hastreiter P, Ertl T. Integrated Registration and Visualization of Medical Image Data. In: Proc. of Computer Graphis International; 1998. p. 78–85.
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© 2006 Springer-Verlag Berlin Heidelberg
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Iserhardt-Bauer, S., Schoell, S., Hammen, T., Stefan, H., Doerfler, A., Hastreiter, P. (2006). Efficient Atlas-Based Analysis of the Hippocampus. In: Handels, H., Ehrhardt, J., Horsch, A., Meinzer, HP., Tolxdorff, T. (eds) Bildverarbeitung für die Medizin 2006. Informatik aktuell. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-32137-3_17
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DOI: https://doi.org/10.1007/3-540-32137-3_17
Publisher Name: Springer, Berlin, Heidelberg
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