Abstract
Whiplash PCR has been proposed as a unique mechanism realizing autonomous inference machines and used in various applications of DNA coumputing. However, it is not easy to increase step sizes within a single molecule because of back annealing. This paper proposes a sheme to cascade results of WPCR from molecules to molecules by using a nicking enzyme. We also show preliminary experiments to produce output fragments continuously from WPCR.
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Matsuda, D., Yamamura, M. (2003). Cascading Whiplash PCR with a Nicking Enzyme. In: Hagiya, M., Ohuchi, A. (eds) DNA Computing. DNA 2002. Lecture Notes in Computer Science, vol 2568. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-36440-4_4
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DOI: https://doi.org/10.1007/3-540-36440-4_4
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