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Selection of Informative Genes in Gene Expression Based Diagnosis: A Nonparametric Approach

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Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 1933))

Abstract

We study a nonparametric approach to cancer classification using data from DNA microarrays. We compare our approach to the approach of [4].

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References

  1. Alizadeh, A. A. et al: Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403 (2000) 503–511

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  2. Ciampi, A. et al: Recursive partioning: a versatile method for exploratory data analysis in Biostatistics. in Biostatistics (eds. I. B. MacNeill and G. J. Umphrey). (1987) D. Reidel Publishing, New York

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  3. Gail, M. H. and Green, S. B.: A generalization of the one-sided two-sample Kolmogorov-Smirnov statistic for evaluating diagnostic tests. Biometrics 32 (1976) 561–570

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  4. Golub, T. R. et al: Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 286 (1999) 531–536

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  5. Miller, R. and Siegmund, D.: Maximally selected chi-square statistics. Biometrics38 (1982) 1011–1016

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  6. Slonim, D. K. et al: Class prediction and discovery using gene expression data. Manuscript available at http://www.genome.wi.mit.edu/MPR

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© 2000 Springer-Verlag Berlin Heidelberg

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Beibel, M. (2000). Selection of Informative Genes in Gene Expression Based Diagnosis: A Nonparametric Approach. In: Brause, R.W., Hanisch, E. (eds) Medical Data Analysis. ISMDA 2000. Lecture Notes in Computer Science, vol 1933. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-39949-6_36

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  • DOI: https://doi.org/10.1007/3-540-39949-6_36

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-41089-8

  • Online ISBN: 978-3-540-39949-0

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