Abstract
In this paper, we present a neural network approach to hierarchical unsupervised clustering of functional magnetic resonance imaging (fMRI) time-sequences of the human brain by self-organized fuzzy minimal free energy vector quantization (VQ). In contrast to conventional model-based fMRI data analysis techniques, this deterministic annealing procedure does not imply presumptive knowledge of expected stimulus-response patterns, and, thus, may be applied to fMRI experiments in which the time course of the stimulus is unknown like in spontaneously occurring events, e.g. hallucinations, epileptic fits, or sleep. Moreover, as minimal free energy VQ represents a hierarchical data analysis strategy implying repetitive cluster splitting, it can provide a natural approach to the subclassification task of activated brain regions on different scales of resolution with respect to fine-grained differences in pixel dynamics.
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References
P.A. Bandettini, A. Jesmanowicz, E.C. Wong, and J.S. Hyde: Processing strategies for time-course data sets in functional MRI of the human brain. Magn. Reson. Med. 30 (1993) 161–173 51
D.R. Dersch: Eigenschaften neuronaler Vektorquantisierer und ihre Anwendung in der Sprachverarbeitung. Verlag Harri Deutsch, Reihe Physik, Bd. 54, Thun, Frankfurt am Main (1996) ISBN 3-8171-1492-3 50, 50, 50
D.R. Dersch, S. Albrecht, and P. Tavan: Hierarchical fuzzy clustering. In A. Wismüller and D.R. Dersch, editors, Symposion über biologische Informationsverarbeitung und Neuronale Netze — SINN’ 95, Konferenzband. Hanns-Seidel-Stiftung, München (1996) 50, 51
D.R. Dersch and P. Tavan: Control of annealing in minimal free energy vector quantization. In Proceedings of the IEEE International Conference on Neural Networks ICNN’94, Orlando, Florida (1994) 698–70350, 51
D.R. Dersch and P. Tavan: Load balanced vector quantization. In Proceedings of the International Conference on Arti.cial Neural Networks ICANN, Springer (1994) 1067–107050, 51, 51
D.R. Dersch and P. Tavan: Asymptotic level density in topological feature maps. IEEE Transactions on Neural Networks 6(1) (1995) 230–236 51
H. Fischer, M. Buechert, and J. Hennig: Assessing the dynamics of fMRI data usingself-organizing map clustering. In Proceedings of the 5th SMR meeting (1997) 50
T. Kohonen: The self-organizing map. Proceedings of the IEEE 78(9) (1990) 1464–1480 50
T.M. Martinetz and K. Schulten: A ‘neural gas’ network learns topologies. In Proceedings of the International Conference on Artificial Neural Networks ICANN, Amsterdam, Elsevier Science Publishers (1991) 397–402 50
K. Rose, E. Gurewitz, and G.C. Fox: Vector quantization by deterministic annealing. IEEE Transactions on Information Theory 38(4) (1992) 1249–1257 50, 50, 51
A. Wismüller and D.R. Dersch: Neural network computation in biomedical research: chances for conceptual cross-fertilization. Theory in Biosciences 116(3) (1997) 49, 50
R.P. Woods, S.R. Cherry, and J.C. Mazziotta: Rapid automated algorithm for aligning and reslicing PET images. Journal of Computer Assisted Tomography 16 (1992) 620–633 51
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Wismüller, A., Dersch, D.R., Lipinski, B., Hahn, K., Auer, D. (2001). Hierarchical Clustering of Functional MRI Time-Series by Deterministic Annealing. In: Brause, R.W., Hanisch, E. (eds) Medical Data Analysis. ISMDA 2000. Lecture Notes in Computer Science, vol 1933. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-39949-6_8
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DOI: https://doi.org/10.1007/3-540-39949-6_8
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