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Binary Vector or Real Value Coding for Secondary Structure Prediction? A Case Study of Polyproline Type II Prediction

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Medical Data Analysis (ISMDA 2001)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 2199))

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Abstract

Amino acid sequences are usually described using categorical variables which are difficult to change to a numerical form. We compare two numerical coding methods in polyproline type II secondary structure predictions, the frequently used binary vector coding method and our new real value coding method based on the PAM250 substitution table which consists of amino acid mutation information. The real value coding method has good properties such as space saving and illustrative form. Our first results are almost comparable to the results of traditional binary vector coding method.

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References

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© 2001 Springer-Verlag Berlin Heidelberg

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Siermala, M., Juhola, M., Vihinen, M. (2001). Binary Vector or Real Value Coding for Secondary Structure Prediction? A Case Study of Polyproline Type II Prediction. In: Crespo, J., Maojo, V., Martin, F. (eds) Medical Data Analysis. ISMDA 2001. Lecture Notes in Computer Science, vol 2199. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45497-7_40

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  • DOI: https://doi.org/10.1007/3-540-45497-7_40

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-42734-6

  • Online ISBN: 978-3-540-45497-7

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