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Separating EEG spike-clusters in epilepsy by a growing and splitting net

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Artificial Neural Networks — ICANN 96 (ICANN 1996)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 1112))

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Abstract

The presurgical evaluation of epilepsy patients relies on an exact localization and delineation of the generators of epileptic seizures. During the registration of the electroencephalogram (EEG) sharp transient signals called spikes can be observed. These spikes give hints for the so called epileptogenic zone in the brain. In order to decide whether these spikes derive from single or multiple generators an incrementing topology preserving map with insertion and deletion of units was trained for the EEG data of individual patients. By deleting of units the net was separated into subnets. Thus it could be further used for vector quantization. The spatial distributions of the peak amplitude of the spikes in all channels as well as the time differences of their peaks were used as input signals. The separation of spatio-temporal clusters of the spikes was compared with those clusters identified by a human reviewer.

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References

  1. Blume, W., Lemieux, J., Morphology of spikes in spike-and-wave complexes, Electroencephalograhy and clinical Neurophysiology 69 (1988), pp 508–515

    Google Scholar 

  2. Elo, P., Saarinen, J., Värri, A., et. al., Classification of Epileptic EEG by Using Self-Organizing Maps, in: Artificial Neural Networks 2, Aleksander, I., Taylor, J., Elsevier, Amsterdam, (1992)

    Google Scholar 

  3. Dümpelmann, M., Hufnagel, A., Burr, W., Elger, C., Determination of the Epileptogenic zone by use of Spike Clustering and Spike-Amplitude-Latency-Topograms, Epilepsia, 35 (Sup. 8) (1994), p 28

    Google Scholar 

  4. Fritzke, B., Vector Quantization in a Growing and Splitting Elastic Net, in: Proc. ICANN'93, Int. Conf. on Artificial Neural Networks, Gielen, S., Kappen, B., Springer, London, (1993)

    Google Scholar 

  5. Fritzke, B., Growing Feature Maps and Growing Cell Structures — a Performance Comparison, in: Advances in Neural Information Processing Systems 5, Giles, L., Hanson, S., Cowan, J., Morgan Kaufmann Publishers, San Mateo, CA, (1993)

    Google Scholar 

  6. Fritzke, B., Growing cell structures — a self-organizing network for unsupervised and supervised learning, Neural Networks 7(9)(1994), pp 1441–1460

    Google Scholar 

  7. Fritzke, B., Fast learning with incremental RBF networks, Neural Processing Letters, 1(1) (1994), pp 2–5

    Google Scholar 

  8. Hufnagel, A., Burr, W., Elger, C., et al., Localization of the epileptic focus during methohexital induced anesthesia, Epilepsia, 33(2) (1992), pp 271–284

    Google Scholar 

  9. Kaski, S., Joutsiniemi, S., Monitoring EEG Signal with the Self-Organizing Map, in: Proc. ICANN'93, Int. Conf. on Artificial Neural Networks, Gielen, S., Kappen, B., Springer, London, (1993)

    Google Scholar 

  10. Kohonen, T., Self-Organization and Associative Memory, Springer Series in Information Sciences 8, Springer, Heidelberg, (1984)

    Google Scholar 

  11. Kohonen, T., The Self-Organizing Map, Proc. IEEE 78 (1990), pp 1464–1480

    Google Scholar 

  12. Kohonen, T., Self-Organizing Maps, Springer Series in Information Sciences 30, Springer, Heidelberg, (1995)

    Google Scholar 

  13. Lopes da Silva, F., Dijk, A., Smits, H., Detection of Nonstationarities in EEGs using the Autoregressive Model. An application to the EEGs of Epileptics, in: CEAN: Computerized EEG-Analysis, Dolce, G., Künkel, H., Fischer, Stuttgart, (1975)

    Google Scholar 

  14. Lüders, H., Awad, I., Conceptual Considerations, in: Epilepsy surgery, Lüders, H., Raven Press, New York, (1992)

    Google Scholar 

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Christoph von der Malsburg Werner von Seelen Jan C. Vorbrüggen Bernhard Sendhoff

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© 1996 Springer-Verlag Berlin Heidelberg

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Dümpelmann, M., Elger, C.E. (1996). Separating EEG spike-clusters in epilepsy by a growing and splitting net. In: von der Malsburg, C., von Seelen, W., Vorbrüggen, J.C., Sendhoff, B. (eds) Artificial Neural Networks — ICANN 96. ICANN 1996. Lecture Notes in Computer Science, vol 1112. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-61510-5_43

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  • DOI: https://doi.org/10.1007/3-540-61510-5_43

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-61510-1

  • Online ISBN: 978-3-540-68684-2

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