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Fitting Points on the Real Line and Its Application to RH Mapping

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Book cover Algorithms — ESA’ 98 (ESA 1998)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 1461))

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Abstract

The Matrix-To-Line problem is that of, given an n × n symmetric matrix D, finding an arrangement of n points on the real line such that the so obtained distances agree as well as possible with the by D specified distances, w.r.t. the max-norm. The Matrix-To-Line problem has previously been shown to be NP-complete [11]. We show that it can be approximated within 2, but not within 4/3 unless P=NP. We also show tight bounds under a stronger assumption. We show that the Matrix-To-Line problem cannot be approximated within 2 − δ unless 3-colorable graphs can be colored with ⌈4/δ⌉ colors in polynomial time. Currently, the best polynomial time algorithm colors a 3-colorable graph with Õ(n 3/14) colors [4].

We apply our Matrix-To-Line algorithm to a problem in computational biology, namely, the Radiation Hybrid (RH) problem, i.e., the algorithmic part of a physical mapping method called RH mapping. This gives us the first algorithm with a guaranteed convergence for the general RH problem.

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© 1998 Springer-Verlag Berlin Heidelberg

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Håstad, J., Ivansson, L., Lagergren, J. (1998). Fitting Points on the Real Line and Its Application to RH Mapping. In: Bilardi, G., Italiano, G.F., Pietracaprina, A., Pucci, G. (eds) Algorithms — ESA’ 98. ESA 1998. Lecture Notes in Computer Science, vol 1461. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-68530-8_39

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  • DOI: https://doi.org/10.1007/3-540-68530-8_39

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  • Print ISBN: 978-3-540-64848-2

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