Definition
An ontology is a formal representation of a set of heterogeneous concepts. However, in the life sciences, the term clinical ontology has also been more broadly defined as also comprising all forms of classified terminologies, including classifications and nomenclatures. Clinical ontologies provide not only a controlled vocabulary but also relationships among concepts allowing computer reasoning such that different parties, like physicians and insurers, can efficiently answer complex queries.
Historical Background
As the life sciences integrates increasingly sophisticated systems of patient management, different means of data representation have had to keep pace to support user systems. Simultaneously, the explosion of genetic information from breakthroughs from the Human Genome Project and gene chip technology have further expedited the need for robust, scalable platforms for handling...
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American Medical Association [cited; Available at: http://www.cptnetwork.com].
American Psychiatric Association [cited; Available at: http://www.psych.org/MainMenu/Research/DSMIV.aspx].
Cimino J.J. Desiderata for controlled medical vocabularies in the twenty-first century. Methods Inf. Med., 37(4–5):394–403, 1998.
Cimino J.J. In defense of the Desiderata. [comment]. J. Biomed. Inform., 39(3):299–306, 2006.
Gruber T.R. Toward principles for the design of ontologies used for knowledge sharing. Int. J. Hum. Comput. Stud., 43(4–5):907–928, 1995.
I.H.T.S.D. [cited; Available from: http://www.ihtsdo.org/our-standards/snomed-ct].
Khan A.N. et al. Standardizing laboratory data by mapping to LOINC. J Am Med Inform Assoc, 13(3):353–355, 2006.
Mahner M. and Kary M. What exactly are genomes, genotypes and phenotypes? And what about phenomes? J. Theor. Biol., 186(1):55–63, 1997.
Musen M.A. et al. PROTEGE-II: computer support for development of intelligent systems from libraries of components. Medinfo, 8 (Pt 1):766–770, 1995.
Nelson S.J., Johnston D., and Humphreys. B.L Relationships in medicical subject headings. In Relationships in the Organization of Knowledge, A.B. Carol, G. Rebecca Dordecht, Kluwer, 2001, pp. 171–184.
World Health Organization [cited; Available at: http://www.who.int/classifications/icd/en/].
World Organization of National Colleges, Academies, and Academic Associations of General Practitioners/Family Physicians, ICPC. International Classification of Primary Care. Oxford University Press, Oxford, 1987.
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Lussier, Y.A., Chen, J.L. (2009). Clinical Ontologies. In: LIU, L., ÖZSU, M.T. (eds) Encyclopedia of Database Systems. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-39940-9_62
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DOI: https://doi.org/10.1007/978-0-387-39940-9_62
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