Definition
MOOSE (Multiscale Object-Oriented Simulation Environment) is a general-purpose biological simulator with an emphasis on systems biology and computational neuroscience.
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Introduction
Mathematical modeling and computer simulations constitute an increasingly important approach for understanding complex biological systems. MOOSE is a modern, free, and open-source software designed for the modeling and simulation of a wide range of detailed biological phenomena spanning many spatial and temporal scales. MOOSE uses standard C++ with a variety of open-source libraries and currently runs on laptops, workstations, and large parallel machines that support Linux.
This section explains the basic features of MOOSE by examining the terms in its acronym: Multiscale Object-Oriented Simulation Environment.
MOOSE is a multiscalesimulator. This means that it can simulate processes at many levels of detail and at many timescales. This includes the movement and interactions...
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References
Andrews SS, Addy NJ, Brent R, Arkin AP (2010) Detailed simulations of cell biology with Smoldyn 2.1. PLoS Comput Biol 6(3):e1000705
Bergmann FT, Shapiro BE, Hucka M (2011) SBML software summary. Resource document. The systems biology markup language editors and team. http://sbml.org/SBML_Software_Guide/SBML_Software_Summary
Bower JM, Beeman D (1998) The book of GENESIS: exploring realistic neural models with the GEneral NEural SImulation System, 2nd edn. Springer, New York
Carnevale NT, Hines ML (2006) The NEURON book. Cambridge University Press, Cambridge, UK
Gleeson P, Crook S, Cannon RC, Hines ML, Billings GO, Farinella M, Morse TM, Davison AP, Ray S, Bhalla US, Barnes SR, Dimitrova YD, Silver RA (2010) NeuroML: a language for describing data driven models of neurons and networks with a high degree of biological detail. PLoS Comput Biol 6(6):e1000815
Hucka M, Bergmann FT, Hoops S, Keating SM, Sahle S, Schaff JC, Smith LP, Wilkinson DJ (2010) The Systems Biology Markup Language (SBML): language specification for level 3 version 1 core. Resource document. http://sbml.org/Special/specifications/sbml-level-3/version-1/core/sbml-level-3-version-1-core.pdf
Mascagni MV, Sherman AS (1998) Numerical methods for neuronal modeling. In: Koch C, Segev I (eds) Methods in neuronal modeling: from ions to networks, 2nd edn. MIT Press, Cambridge, pp 569–606
Ray S, Bhalla US (2008) PyMOOSE: interoperable scripting in python for MOOSE. Front Neuroinform 2:6
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Dudani, N., Bhalla, U.S., Ray, S. (2014). MOOSE, the Multiscale Object-Oriented Simulation Environment. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_257-1
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DOI: https://doi.org/10.1007/978-1-4614-7320-6_257-1
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Publisher Name: Springer, New York, NY
Online ISBN: 978-1-4614-7320-6
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