Definition
An electronic system, usually comprised of external and implanted components, that can sense light, convert light to an electronic signal, and apply that signal to the retina, as a treatment for blindness secondary to photoreceptor loss.
Introduction
In a healthy retina, light is detected by photoreceptors (rods and cones) via photosensitive molecules in the outer segments of the photoreceptors. These molecules, once transformed by light, trigger a cascade of neurochemical events that lead to other neural cells in the retina (ganglion cells), sending signals to the downstream visual centers of the brain. Retinal degenerative diseases, like retinitis pigmentosa and age-related macular degeneration, affect primarily photoreceptors, leaving the retina unable to sense light, but remaining neurons in the retina (bipolar cells and ganglion cells) can be...
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References
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Weiland, J. (2014). Vision Prosthesis. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_563-1
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DOI: https://doi.org/10.1007/978-1-4614-7320-6_563-1
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Publisher Name: Springer, New York, NY
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