Abstract
Hospital readmission refers to the situation where a patient is re-hospitalized with the same primary diagnosis after discharge. It causes $26 billion preventable expense to the U.S. health systems annually and may indicate suboptimal care for patients. Predicting readmission risk is essential to alleviate such financial and medical consequences. Yet such prediction is challenging due to the dynamic and complex nature of the hospitalization trajectory. The state-of-the-art studies apply statistical models with unified parameters for all patients and use static predictors in a period, failing to consider patients’ heterogeneous illness trajectories. Our approach – TADEL (Trajectory-BAsed DEep Learning) – addresses the present challenge and captures various illness trajectories. We evaluate TADEL on a unique five-year national Medicare claims dataset, reaching a precision of 0.780, a recall of 0.985, and an F1-score of 0.870. This study contributes to IS literature and methodology by formulating the readmission prediction problem and developing a novel personalized readmission risk prediction framework. This framework provides direct implications for health providers to assess patients’ readmission risk and take early interventions to avoid potential negative consequences.
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References
Axon, R.N., Williams, M.V.: Hospital readmission as an accountability measure. JAMA 305(5), 504 (2011)
Bardhan, I., Oh, J.H.C., Zheng, Z.E., Kirksey, K.: Predictive analytics for readmission of patients with congestive heart failure. Inf. Syst. Res. 26(1), 19–39 (2015)
Bottle, A., Aylin, P., Majeed, A.: Identifying patients at high risk of emergency hospital admissions: a logistic regression analysis. J. R. Soc. Med. 99(8), 406–414 (2006)
Brännström, J., Sönnerborg, A., Svedhem, V., Neogi, U., Marrone, G.: A high rate of HIV-1 acquisition post immigration among migrants in Sweden determined by a CD4 T-cell decline trajectory model. HIV Med. 18(9), 677–684 (2017)
Center for Health Information and Analysis: Performance of the Massachusetts Health Care System Series: A Focus on Provider Quality (2015)
Chen, R., et al.: Cloud-based predictive modeling system and its application to asthma readmission prediction. In: AMIA Annual Symposium Proceedings. AMIA Symposium vol. 2015, pp. 406–415 (2015)
Coleman, E.A., Min, S.J., Chomiak, A., Kramer, A.M.: Posthospital care transitions: patterns, complications, and risk identification. Health Serv. Res. 39(5), 1449–1466 (2004)
Corbin, J.M., Strauss, A.: A nursing model for chronic illness management based upon the trajectory framework. Sch. Inq. Nurs. Pract. 5, 155–1774 (1991)
Dhalla, I.A., et al.: Effect of a postdischarge virtual ward on readmission or death for high-risk patients. JAMA 312(13), 1305 (2014)
Donnelly, C., McFetridge, L.M., Marshall, A.H., Mitchell, H.J.: A two-stage approach to the joint analysis of longitudinal and survival data utilising the Coxian phase-type distribution. Stat. Methods Med. Res. (2017) https://doi.org/10.1177/0962280217706727
Glance, L.G., et al.: Hospital readmission after noncardiac surgery. JAMA Surg. 149(5), 439 (2014)
Halfon, P., Eggli, Y., Pêtre-Rohrbach, I., Meylan, D., Marazzi, A., Burnand, B.: Validation of the potentially avoidable hospital readmission rate as a routine indicator of the quality of hospital care. Med. Care 44(11), 972–981 (2006)
Hammill, B.G., et al.: Incremental value of clinical data beyond claims data in predicting 30-day outcomes after heart failure hospitalization. Circ. Cardiovasc. Qual. Outcomes 4(1), 60–67 (2011)
Hasan, O., et al.: Hospital readmission in general medicine patients: a prediction model. J. Gen. Intern. Med. 25(3), 211–219 (2010)
Holman, C.D.J., Preen, D.B., Baynham, N.J., Finn, J.C., Semmens, J.B.: A multipurpose comorbidity scoring system performed better than the Charlson index. J. Clin. Epidemiol. 58(10), 1006–1014 (2005)
Howell, S., Coory, M., Martin, J., Duckett, S.: Using routine inpatient data to identify patients at risk of hospital readmission. BMC Health Serv. Res. 9(1), 96 (2009)
Hser, Y.I., Longshore, D., Anglin, M.D.: The life course perspective on drug use. Eval. Rev. 31(6), 515–547 (2007)
Jovanovic, M., Radovanovic, S., Vukicevic, M., Van Poucke, S., Delibasic, B.: Building interpretable predictive models for pediatric hospital readmission using Tree-Lasso logistic regression. Artif. Intell. Med. 72, 12–21 (2016)
Kansagara, D., et al.: Risk prediction models for hospital readmission. JAMA 306(15), 1688 (2011)
Krumholz, H.M., et al.: Patterns of hospital performance in acute myocardial infarction and heart failure 30-day mortality and readmission. Circ. Cardiovasc. Qual. Outcomes 2(5), 407–413 (2009)
Mishel, M.H.: Reconceptualization of the uncertainty in illness theory. Image J. Nurs. Scholarsh. 22(4), 256–262 (1990)
Paul, S.S., et al.: Two-year trajectory of fall risk in people with parkinson disease: a latent class analysis. Arch. Phys. Med. Rehabil. 97(3), 372–379.e1 (2016)
Radovanovic, S., Vukicevic, M., Kovacevic, A., Stiglic, G., Obradovic, Z.: Domain knowledge based hierarchical feature selection for 30-day hospital readmission prediction. In: Holmes, John H., Bellazzi, R., Sacchi, L., Peek, N. (eds.) AIME 2015. LNCS (LNAI), vol. 9105, pp. 96–100. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-19551-3_11
Shadmi, E., Flaks-Manov, N., Hoshen, M., Goldman, O., Bitterman, H., Balicer, R.D.: Predicting 30-day readmissions with preadmission electronic health record data. Med. Care 53(3), 283–289 (2015)
Silverstein, M.D., Qin, H., Mercer, S.Q., Fong, J., Haydar, Z.: Risk factors for 30-day hospital readmission in patients ≥65 years of age. Proc. (Bayl. Univ. Med. Cent.) 21(4), 363–372 (2008)
Vukicevic, M., Radovanovic, S., Kovacevic, A., Stiglic, G., Obradovic, Z.: Improving hospital readmission prediction using domain knowledge based virtual examples. In: Uden, L., Heričko, M., Ting, I.-H. (eds.) KMO 2015. LNBIP, vol. 224, pp. 695–706. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-21009-4_51
van Walraven, C., et al.: Derivation and validation of an index to predict early death or unplanned readmission after discharge from hospital to the community. CMAJ 182(6), 551–557 (2010)
Woog, P.: The Chronic Illness Trajectory Framework: The Corbin and Strauss Nursing Model. Springer Publishing Company, New York (1992)
Xie, J., Liu, X., Zeng, D.D.: Mining e-cigarette adverse events in social media using Bi-LSTM recurrent neural network with word embedding representation. J. Am. Med. Inform. Assoc. 25, 72–80 (2017)
Yu, S., Farooq, F., Esbroeck, A., Fung, G., Anand, V., Krishnapuram, B.: Predicting readmission risk with institution-specific prediction models. Artif. Intell. Med. 65(2), 89–96 (2015)
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Xie, J., Zhang, B., Zeng, D. (2018). Readmission Prediction Using Trajectory-Based Deep Learning Approach. In: Chen, H., Fang, Q., Zeng, D., Wu, J. (eds) Smart Health. ICSH 2018. Lecture Notes in Computer Science(), vol 10983. Springer, Cham. https://doi.org/10.1007/978-3-030-03649-2_22
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