Abstract
A multi-analyte biosensing platform for the selective label-free detection of protein biomarkers has been designed through a three-dimensional model based on the finite element method. The sensing element of the platform is a planar plasmonic nanocavity, consisting of a one-dimensional periodic structure (Bragg grating) in gold, with a defect, placed on the buried oxide of a silicon-on-insulator substrate. The footprint of this sensing element, which has a good chemical stability, is only 1.57 μm2. The sensor has a detection limit of 128 pg/mm2 and a surface sensitivity of 1.8 nm/nm.
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Dell’Olio, F., Conteduca, D., De Palo, M., Sasanelli, N., Ciminelli, C. (2019). Design of a Label-Free Multiplexed Biosensing Platform Based on an Ultracompact Plasmonic Resonant Cavity. In: Andò, B., et al. Sensors. CNS 2018. Lecture Notes in Electrical Engineering, vol 539. Springer, Cham. https://doi.org/10.1007/978-3-030-04324-7_34
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DOI: https://doi.org/10.1007/978-3-030-04324-7_34
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