Abstract
Systems biology aims at understanding an organism in its entirety. This objective can only be achieved with the joint effort of specialized work groups. These collaborating groups need a centralized platform for data exchange. Instead data is often uncoordinatedly managed using heterogeneous data formats. Such circumstances present a major hindrance to gaining a global understanding of the data and to automating analysis routines.
DISBi is a framework for creating an integrated online environment that solves these problems. It enables researchers to filter, integrate and analyze data directly in the browser. A DISBi application dynamically adapts to its data model. Thus DISBi offers a solution for a wide range of systems biology projects.
An example installation is available at disbi.org. Source code and documentation are available from https://github.com/DISBi/django-disbi.
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Acknowledgements
The authors thank Meina Neumann-Schaal for critical reading of the manuscript and four anonymous reviewer for their instructive comments. Rüdiger Busche thanks Pascal Nieters for support in the publication process.
This work was supported by the Federal State of Lower Saxony, Niedersächsisches Vorab (VWZN2889)/3215.
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Busche, R., Dannheim, H., Schomburg, D. (2019). DISBi: A Flexible Framework for Integrating Systems Biology Data. In: Auer, S., Vidal, ME. (eds) Data Integration in the Life Sciences. DILS 2018. Lecture Notes in Computer Science(), vol 11371. Springer, Cham. https://doi.org/10.1007/978-3-030-06016-9_10
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