Abstract
The ABCD Neurocognitive Prediction Challenge (ABCD-NP-Challenge 2019) made available T1-weighted structural scans for children alongside their fluid intelligence scores. The goal of the challenge was to use this anatomical brain data to train a model that could be successful in predicting fluid intelligence scores from held-out T1-weighted structural scans taken of other children. Functional magnetic resonance imaging (fMRI) has been moderately successful at identifying neural correlates of cognitive functioning, including intelligence. This study sought to leverage anatomical metrics within functionally defined regions, convolutional neural networks, and regression models to predict fluid intelligence. The proposed model performed competitively on the ABCD-NP-Challenge, and significantly outperformed a non deep-learning approach for behavior prediction based on the LASSO.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Baldassarre, A., Lewis, C.M., Committeri, G., Snyder, A.Z., Romani, G.L., Corbetta, M.: Individual variability in functional connectivity predicts performance of a perceptual task. Proc. Natl. Acad. Sci. 109(9), 3516–3521 (2012)
Bernal, J., et al.: Deep convolutional neural networks for brain image analysis on magnetic resonance imaging: a review. Artif. Intell. Med. 95, 64–81 (2018)
Carr, L., Iacoboni, M., Dubeau, M.C., Mazziotta, J.C., Lenzi, G.L.: Neural mechanisms of empathy in humans: a relay from neural systems for imitation to limbic areas. Proc. Natl. Acad. Sci. 100(9), 5497–5502 (2003)
Christov-Moore, L., Iacoboni, M.: Self-other resonance, its control and prosocial inclinations: brain-behavior relationships. Hum. Brain Mapp. 37(4), 1544–1558 (2016)
Cole, M.W., Yarkoni, T., Repovš, G., Anticevic, A., Braver, T.S.: Global connectivity of prefrontal cortex predicts cognitive control and intelligence. J. Neurosci. 32(26), 8988–8999 (2012)
Ding, J., Li, A., Hu, Z., Wang, L.: Accurate pulmonary nodule detection in computed tomography images using deep convolutional neural networks. In: Descoteaux, M., Maier-Hein, L., Franz, A., Jannin, P., Collins, D.L., Duchesne, S. (eds.) MICCAI 2017. LNCS, vol. 10435, pp. 559–567. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-66179-7_64
Dosenbach, N.U., et al.: Prediction of individual brain maturity using fMRI. Science 329(5997), 1358–1361 (2010)
Jenkinson, M., Bannister, P., Brady, M., Smith, S.: Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage 17(2), 825–841 (2002)
Jenkinson, M., Smith, S.: A global optimisation method for robust affine registration of brain images. Med. Image Anal. 5(2), 143–156 (2001)
Kingma, D.P., Ba, J.: Adam: a method for stochastic optimization. arXiv preprint arXiv:1412.6980 (2014)
Louw, N., Steel, S.: Variable selection in Kernel Fisher discriminant analysis by means of recursive feature elimination. Comput. Stat. Data Anal. 51(3), 2043–2055 (2006)
Noble, K.G., Houston, S.M., Kan, E., Sowell, E.R.: Neural correlates of socioeconomic status in the developing human brain. Dev. Sci. 15(4), 516–527 (2012)
Patenaude, B., Smith, S.M., Kennedy, D.N., Jenkinson, M.: A bayesian model of shape and appearance for subcortical brain segmentation. Neuroimage 56(3), 907–922 (2011)
Power, J.D., et al.: Functional network organization of the human brain. Neuron 72(4), 665–678 (2011)
Reggente, N., et al.: Multivariate resting-state functional connectivity predicts response to cognitive behavioral therapy in obsessive-compulsive disorder. Proc. Natl. Acad. Sci. 115(9), 2222–2227 (2018)
Rohlfing, T., Zahr, N.M., Sullivan, E.V., Pfefferbaum, A.: The SRI24 multichannel atlas of normal adult human brain structure. Hum. Brain Mapp. 31(5), 798–819 (2010)
Smith, S.M., et al.: Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 23, S208–S219 (2004)
Volkow, N.D., et al.: The conception of the ABCD study: from substance use to a broad NIH collaboration. Dev. Cogn. Neurosci. 32, 4–7 (2018)
Author information
Authors and Affiliations
Corresponding authors
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this paper
Cite this paper
Chiang, J.N., Reggente, N., Dell’Italia, J., Zheng, Z.S., Lutkenhoff, E.S. (2019). Predicting Fluid Intelligence Using Anatomical Measures Within Functionally Defined Brain Networks. In: Pohl, K., Thompson, W., Adeli, E., Linguraru, M. (eds) Adolescent Brain Cognitive Development Neurocognitive Prediction. ABCD-NP 2019. Lecture Notes in Computer Science(), vol 11791. Springer, Cham. https://doi.org/10.1007/978-3-030-31901-4_17
Download citation
DOI: https://doi.org/10.1007/978-3-030-31901-4_17
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-31900-7
Online ISBN: 978-3-030-31901-4
eBook Packages: Computer ScienceComputer Science (R0)