Abstract
Lesion detection in CT (computed tomography) scan images is an important yet challenging task due to the low contrast of soft tissues and similar appearance between lesion and the background. Exploiting 3D context information has been studied extensively to improve detection accuracy. However, previous methods either use a 3D CNN which usually requires a sliding window strategy to inference and only acts on local patches; or simply concatenate feature maps of independent 2D CNNs to obtain 3D context information, which is less effective to capture 3D knowledge. To address these issues, we design a hybrid detector to combine benefits from both of the above methods. We propose to build several light-weighted 3D CNNs as subnets to bridge 2D CNNs’ intermediate features, so that 2D CNNs are connected with each other which interchange 3D context information while feed-forwarding. Comprehensive experiments in DeepLesion dataset show that our method can combine 3D knowledge effectively and provide higher quality backbone features. Our detector surpasses the current state-of-the-art by a large margin with comparable speed and GPU memory consumption.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Dai, J., Li, Y., He, K., Sun, J.: R-FCN: object detection via region-based fully convolutional networks. In: NIPS, pp. 379–387 (2016)
Ding, J., Li, A., Hu, Z., Wang, L.: Accurate pulmonary nodule detection in computed tomography images using deep convolutional neural networks. In: Descoteaux, M., Maier-Hein, L., Franz, A., Jannin, P., Collins, D.L., Duchesne, S. (eds.) MICCAI 2017. LNCS, vol. 10435, pp. 559–567. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-66179-7_64
He, K., Gkioxari, G., Dollár, P., Girshick, R.: Mask R-CNN. In: ICCV, pp. 2961–2969 (2017)
Liao, F., Liang, M., Li, Z., Hu, X., Song, S.: Evaluate the malignancy of pulmonary nodules using the 3D deep leaky noisy-or network. arXiv preprint arXiv:1711.08324 (2017)
Liu, W., Anguelov, D., Erhan, D., Szegedy, C., Reed, S., Fu, C.-Y., Berg, A.C.: SSD: single shot multibox detector. In: Leibe, B., Matas, J., Sebe, N., Welling, M. (eds.) ECCV 2016. LNCS, vol. 9905, pp. 21–37. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46448-0_2
Redmon, J., Divvala, S., Girshick, R., Farhadi, A.: You only look once: unified, real-time object detection. In: CVPR, pp. 779–788 (2016)
Ren, S., He, K., Girshick, R., Sun, J.: Faster R-CNN: towards real-time object detection with region proposal networks. In: NIPS, pp. 91–99 (2015)
Setio, A.A.A., et al.: Validation, comparison, and combination of algorithms for automatic detection of pulmonary nodules in computed tomography images: the luna16 challenge. Med. Image Anal. 42, 1–13 (2017)
Simonyan, K., Zisserman, A.: Very deep convolutional networks for large-scale image recognition. arXiv preprint arXiv:1409.1556 (2014)
Yan, K., Bagheri, M., Summers, R.M.: 3D context enhanced region-based convolutional neural network for end-to-end lesion detection. In: Frangi, A.F., Schnabel, J.A., Davatzikos, C., Alberola-López, C., Fichtinger, G. (eds.) MICCAI 2018. LNCS, vol. 11070, pp. 511–519. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00928-1_58
Yan, K., et al.: Deep lesion graphs in the wild: relationship learning and organization of significant radiology image findings in a diverse large-scale lesion database. In: CVPR, pp. 9261–9270 (2018)
Acknowledgements
This work was supported by the Lustgarten Foundation for Pancreatic Cancer Research and NSFC No. 61672336.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this paper
Cite this paper
Zhang, Z., Zhou, Y., Shen, W., Fishman, E., Yuille, A. (2019). Lesion Detection by Efficiently Bridging 3D Context. In: Suk, HI., Liu, M., Yan, P., Lian, C. (eds) Machine Learning in Medical Imaging. MLMI 2019. Lecture Notes in Computer Science(), vol 11861. Springer, Cham. https://doi.org/10.1007/978-3-030-32692-0_54
Download citation
DOI: https://doi.org/10.1007/978-3-030-32692-0_54
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-32691-3
Online ISBN: 978-3-030-32692-0
eBook Packages: Computer ScienceComputer Science (R0)