Skip to main content

Guided M-Net for High-Resolution Biomedical Image Segmentation with Weak Boundaries

  • Conference paper
  • First Online:
Book cover Ophthalmic Medical Image Analysis (OMIA 2019)

Abstract

Biomedical image segmentation plays an important role in automatic disease diagnosis. However, some particular biomedical images have blurred object boundaries, and may contain noises due to the limited performance of imaging device. This issue will highly affects segmentation performance, and will become even severer when images have to be resized to lower resolution on a machine with limited memory. To address this, we propose a guide-based model, called G-MNet, which seeks to exploit edge information from guided map to guide the corresponding lower resolution outputs. The guided map is generated from multi-scale input to provide a better guidance. In these ways, the segmentation model will be more robust to noises and blurred object boundaries. Extensive experiments on two biomedical image datasets demonstrate the effectiveness of the proposed method.

This work was done when S. Zhang and Y. Yan are interns at CVTE Research.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Chaurasia, A., Culurciello, E.: LinkNet: exploiting encoder representations for efficient semantic segmentation. In: VCIP. IEEE (2017)

    Google Scholar 

  2. Chen, L.C., et al.: DeepLab: semantic image segmentation with deep convolutional nets, atrous convolution, and fully connected CRFs. TPAMI 40, 834–848 (2018)

    Article  Google Scholar 

  3. Chen, Q., et al.: Fast image processing with fully-convolutional networks. In: ICCV (2017)

    Google Scholar 

  4. Cheng, J., et al.: Superpixel classification based optic disc and optic cup segmentation for glaucoma screening. TMI 32, 1019–1032 (2013)

    Google Scholar 

  5. Fu, H., et al.: Joint optic disc and cup segmentation based on multi-label deep network and polar transformation. TMI 37, 1597–1605 (2018)

    Google Scholar 

  6. He, K., et al.: Guided image filtering. TPAMI 35, 1397–1409 (2013)

    Article  Google Scholar 

  7. Hu, P., et al.: Deep level sets for salient object detection. In: CVPR (2017)

    Google Scholar 

  8. Long, J., et al.: Fully convolutional networks for semantic segmentation. In: CVPR (2015)

    Google Scholar 

  9. Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  10. Sun, X., et al.: Localizing optic disc and cup for glaucoma screening via deep object detection networks. In: Stoyanov, D., et al. (eds.) OMIA/COMPAY -2018. LNCS, vol. 11039, pp. 236–244. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00949-6_28

    Chapter  Google Scholar 

  11. Wong, A.L., et al.: Quantitative assessment of lens opacities with anterior segment optical coherence tomography. Br. J. Ophthalmol. 93, 61–65 (2009)

    Article  Google Scholar 

  12. Wu, H., et al.: Fast end-to-end trainable guided filter. In: CVPR (2018)

    Google Scholar 

  13. Xu, Y., et al.: Sliding window and regression based cup detection in digital fundus images for glaucoma diagnosis. In: Fichtinger, G., Martel, A., Peters, T. (eds.) MICCAI 2011. LNCS, vol. 6893, pp. 1–8. Springer, Heidelberg (2011). https://doi.org/10.1007/978-3-642-23626-6_1

    Chapter  Google Scholar 

  14. Yin, F., et al.: Model-based optic nerve head segmentation on retinal fundus images. In: EMBC. IEEE (2011)

    Google Scholar 

  15. Yin, P., et al.: Automatic segmentation of cortex and nucleus in anterior segment OCT images. In: Stoyanov, D., et al. (eds.) OMIA/COMPAY -2018. LNCS, vol. 11039, pp. 269–276. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00949-6_32

    Chapter  Google Scholar 

  16. Zhao, H., et al.: Pyramid scene parsing network. In: CVPR, pp. 2881–2890 (2017)

    Google Scholar 

Download references

Acknowledgements

This work was supported by National Natural Science Foundation of China (NSFC) 61602185 and 61876208, Guangdong Introducing Innovative and Enterpreneurial Teams 2017ZT07X183, and Guangdong Provincial Scientific and Technological Fund 2018B010107001, 2017B090901008 and 2018B010108002, and Pearl River S&T Nova Program of Guangzhou 201806010081, and CCF-Tencent Open Research Fund RAGR20190103, and National Key R&D Program of China #2017YFC0112404.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mingkui Tan .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Zhang, S. et al. (2019). Guided M-Net for High-Resolution Biomedical Image Segmentation with Weak Boundaries. In: Fu, H., Garvin, M., MacGillivray, T., Xu, Y., Zheng, Y. (eds) Ophthalmic Medical Image Analysis. OMIA 2019. Lecture Notes in Computer Science(), vol 11855. Springer, Cham. https://doi.org/10.1007/978-3-030-32956-3_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-32956-3_6

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-32955-6

  • Online ISBN: 978-3-030-32956-3

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics