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Epileptic Seizure Prediction Based on Convolutional Recurrent Neural Network with Multi-Timescale

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Intelligence Science and Big Data Engineering. Big Data and Machine Learning (IScIDE 2019)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 11936))

Abstract

Epilepsy is a common disease that is caused by abnormal discharge of neurons in the brain. The most existing methods for seizure prediction rely on multi kinds of features. To discriminate pre-ictal from inter-ictal patterns of EEG signals, a convolutional recurrent neural network with multi-timescale (MT-CRNN) is proposed for seizure prediction. The network model is built to complement the patient-specific seizure prediction approaches. We firstly calculate the correlation coefficients in eight frequency bands from segmented EEG to highlight the key bands among different people. Then CNN is used to extract features and reduce the data dimension, and the output of CNN acts as input of RNN to learn the implicit relationship of the time series. Furthermore, considering that EEG in different time scales reflect neuron activity in distinct scope, we combine three timescale segments of 1 s, 2 s and 3 s. Experiments are done to validate the performance of the proposed model on the dataset of CHB-MIT, and a promising result of 94.8% accuracy, 91.7% sensitivity, and 97.7% specificity are achieved.

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References

  1. Kannathal, N., Choo, M.L., Acharya, U.R., et al.: Entropies for detection of epilepsy in EEG. Comput. Methods Programs Biomed. 80(3), 187–194 (2005)

    Article  Google Scholar 

  2. Altunay, S., Telatar, Z., Erogul, O.: Epileptic EEG detection using the linear prediction error energy. Expert Syst. Appl. 37(8), 5661–5665 (2010)

    Article  Google Scholar 

  3. Lehnertz, K., Mormann, F., Kreuz, T., et al.: Seizure prediction by nonlinear EEG analysis. IEEE Eng. Med. Biol. Mag. 22(1), 57–63 (2003)

    Article  Google Scholar 

  4. Mormann, F., Andrzejak, R.G., Elger, C.E., et al.: Seizure prediction: the long and winding road. Brain 130(2), 314–333 (2006)

    Article  Google Scholar 

  5. Alotaiby, T.N., Alshebeili, S.A., Alshawi, T., et al.: EEG seizure detection and prediction algorithms: a survey. EURASIP J. Adv. Sig. Process. 2014(1), 183 (2014)

    Article  Google Scholar 

  6. Ahammad, N., Fathima, T., Joseph, P.: Detection of epileptic seizure event and onset using EEG. BioMed Res. Int. 2014 (2014)

    Article  Google Scholar 

  7. Cho, D., Min, B., Kim, J., et al.: EEG-based prediction of epileptic seizures using phase synchronization elicited from noise-assisted multivariate empirical mode decomposition. IEEE Trans. Neural Syst. Rehabil. Eng. 25(8), 1309–1318 (2017)

    Article  Google Scholar 

  8. Kitano, L.A.S., Sousa, M.A.A., Santos, S.D., Pires, R., Thome-Souza, S., Campo, A.B.: Epileptic seizure prediction from EEG signals using unsupervised learning and a polling-based decision process. In: Kůrková, V., Manolopoulos, Y., Hammer, B., Iliadis, L., Maglogiannis, I. (eds.) ICANN 2018. LNCS, vol. 11140, pp. 117–126. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-01421-6_12

    Chapter  Google Scholar 

  9. Cui, S., Duan, L., Qiao, Y., et al.: Learning EEG synchronization patterns for epileptic seizure prediction using bag-of-wave features. J. Ambient Intell. Hum. Comput., 1–16 (2018)

    Google Scholar 

  10. Park, Y., Luo, L., Parhi, K.K., et al.: Seizure prediction with spectral power of EEG using cost-sensitive support vector machines. Epilepsia 52(10), 1761–1770 (2011)

    Article  Google Scholar 

  11. Xiang, J., Li, C., Li, H., et al.: The detection of epileptic seizure signals based on fuzzy entropy. J. Neurosci. Methods 243, 18–25 (2015)

    Article  Google Scholar 

  12. He, K., Zhang, X., Ren, S., et al.: Deep residual learning for image recognition. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 770–778 (2016)

    Google Scholar 

  13. Vaswani, A., Shazeer, N., Parmar, N., et al.: Attention is all you need. In: Advances in Neural Information Processing Systems, pp. 5998–6008 (2017)

    Google Scholar 

  14. Girshick, R.: Fast R-CNN. In: Proceedings of the IEEE International Conference on Computer Vision, pp. 1440–1448 (2015)

    Google Scholar 

  15. Thodoroff, P., Pineau, J., Lim, A.: Learning robust features using deep learning for automatic seizure detection. In: Machine Learning for Healthcare Conference, pp. 178–190 (2016)

    Google Scholar 

  16. Truong, N.D., Nguyen, A.D., Kuhlmann, L., et al.: A generalised seizure prediction with convolutional neural networks for intracranial and scalp electroencephalogram data analysis. arXiv preprint arXiv:1707.01976 (2017)

  17. Mirowski, P., Madhavan, D., LeCun, Y., et al.: Classification of patterns of EEG synchronization for seizure prediction. Clin. Neurophysiol. 120(11), 1927–1940 (2009)

    Article  Google Scholar 

  18. Ma, X., Qiu, S., Zhang, Y., Lian, X., He, H.: Predicting epileptic seizures from intracranial EEG using LSTM-based multi-task learning. In: Lai, J.-H., et al. (eds.) PRCV 2018. LNCS, vol. 11257, pp. 157–167. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-03335-4_14

    Chapter  Google Scholar 

  19. Xun, G., Jia, X., Zhang, A.: Detecting epileptic seizures with electroencephalogram via a context-learning model. BMC Med. Inform. Decis. Mak. 16(2), 70 (2016)

    Article  Google Scholar 

  20. Tsiouris, Κ.Μ., Pezoulas, V.C., Zervakis, M., et al.: A Long Short-Term Memory deep learning network for the prediction of epileptic seizures using EEG signals. Comput. Biol. Med. 99, 24–37 (2018)

    Article  Google Scholar 

  21. Acharya, U.R., Oh, S.L., Hagiwara, Y., et al.: Deep convolutional neural network for the automated detection and diagnosis of seizure using EEG signals. Comput. Biol. Med. 100, 270–278 (2018)

    Article  Google Scholar 

  22. Hussein, R., Palangi, H., Ward, R., et al.: Epileptic seizure detection: a deep learning approach. arXiv preprint arXiv:1803.09848 (2018)

  23. Bashivan, P., Rish, I., Yeasin, M., et al.: Learning representations from EEG with deep recurrent-convolutional neural networks. arXiv preprint arXiv:1511.06448 (2015)

  24. Fei, K., Wang, W., Yang, Q., et al.: Chaos feature study in fractional Fourier domain for preictal prediction of epileptic seizure. Neurocomputing 249, 290–298 (2017)

    Article  Google Scholar 

  25. CHB-mit scalp EEG database, Physionet.org. https://www.physionet.org/pn6/chbmit

  26. Goldberger, A.L., et al.: PhysioBank, PhysioToolkit, and PhysioNet: components of a new research resource for complex physiologic signals. Circulation 101(23), e215–e220 (2000)

    Article  Google Scholar 

  27. Tsiouris, K.M., Pezoulas, V.C., Koutsouris, D.D., et al.: Discrimination of preictal and interictal brain states from long-term EEG data. In: 2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS), pp. 318–323. IEEE (2017)

    Google Scholar 

  28. Zhang, Z., Parhi, K.K.: Low-complexity seizure prediction from iEEG/sEEG using spectral power and ratios of spectral power. IEEE Trans. Biomed. Circuits Syst. 10(3), 693–706 (2016)

    Article  Google Scholar 

  29. Lin, Z., Feng, M., Santos, C.N., et al.: A structured self-attentive sentence embedding. arXiv preprint arXiv:1703.03130 (2017)

  30. Devlin, J., Chang, M.W., Lee, K., et al.: BERT: pre-training of deep bidirectional transformers for language understanding. arXiv preprint arXiv:1810.04805 (2018)

  31. Xing, C., Wu, Y., Wu, W., et al.: Hierarchical recurrent attention network for response generation. In: Thirty-Second AAAI Conference on Artificial Intelligence (2018)

    Google Scholar 

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Acknowledgements

This research is partially sponsored by National Natural Science Foundation of China (No. 61672070 ,61572004), the Project of Beijing Municipal Education Commission (No. KZ201910005008,KM201911232003), the Research Fund from Beijing Innovation Center for Future Chips (No. KYJJ2018004).

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Correspondence to Yuanhua Qiao .

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Duan, L., Hou, J., Qiao, Y., Miao, J. (2019). Epileptic Seizure Prediction Based on Convolutional Recurrent Neural Network with Multi-Timescale. In: Cui, Z., Pan, J., Zhang, S., Xiao, L., Yang, J. (eds) Intelligence Science and Big Data Engineering. Big Data and Machine Learning. IScIDE 2019. Lecture Notes in Computer Science(), vol 11936. Springer, Cham. https://doi.org/10.1007/978-3-030-36204-1_11

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  • DOI: https://doi.org/10.1007/978-3-030-36204-1_11

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