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Automatic Detection of Free Intra-abdominal Air in Computed Tomography

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Medical Image Computing and Computer Assisted Intervention – MICCAI 2020 (MICCAI 2020)

Abstract

Pneumoperitoneum, the presence of air within the peritoneal cavity, is a comparatively rare but potentially urgent critical finding in patients presenting with acute abdominal pain. When prior laparoscopic treatment can be ruled out as a cause, it can indicate perforation of the wall of a hollow organ, which typically necessitates immediate surgery. Computed tomography (CT) is the gold standard for detecting free intra-abdominal air, yet subtle cases are easy to miss. More crucially though, if there is no initial suspicion of pneumoperitoneum, the scans may not be read immediately as other emergency patients take precedence. Therefore, fully automatic detection would provide a direct clinical benefit. In this work, an algorithm for this purpose is proposed which follows a sliding-window approach and has a deep-learning based classifier at its core. In addition to the baseline method, variants that rely on multi-scale inputs and recurrent layers to increase robustness are presented. In a five-fold cross validation on the training data, consisting in abdominal CT scans of 110 affected patients and 29 controls, our method achieved an area under the receiver-operating characteristic curve of 89% for case-level classification. Due to its high specificity at reasonable detection rates, it shows potential for use in triage, where false alerts are considered particularly harmful as they may disrupt the clinical workflow.

O. Taubmann and J. Li—Contributed equally to this work.

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References

  1. Bulas, D.I., Taylor, G.A., Eichelberger, M.R.: The value of CT in detecting bowel perforation in children after blunt abdominal trauma. Am. J. Roentgenol. 153(3), 561–564 (1989)

    Article  Google Scholar 

  2. Cho, K., et al.: Learning phrase representations using RNN encoder-decoder for statistical machine translation. arXiv preprint arXiv:1406.1078 (2014)

  3. Cho, S.-J., et al.: Clinical significance of intraperitoneal air on computed tomography scan after endoscopic submucosal dissection in patients with gastric neoplasms. Surg. Endosc. 28(1), 307–313 (2013). https://doi.org/10.1007/s00464-013-3188-9

    Article  Google Scholar 

  4. Fawcett, T.: An introduction to ROC analysis. Pattern Recogn. Lett. 27(8), 861–874 (2006)

    Article  MathSciNet  Google Scholar 

  5. Hainaux, B., et al.: Accuracy of MDCT in predicting site of gastrointestinal tract perforation. Am. J. Roentgenol. 187(5), 1179–1183 (2006)

    Article  Google Scholar 

  6. Kingma, D.P., Ba, J.: Adam: a method for stochastic optimization. arXiv preprint arXiv:1412.6980 (2014)

  7. Luo, J.W., Lie, J.L., Chong, J.: Pneumoperitoneum on chest X-ray: a DCNN approach to automated detection and localization utilizing salience and class activation maps. In: SIIM Conference on Machine Intelligence in Medical Imaging (2018)

    Google Scholar 

  8. Matthews, B.W.: Comparison of the predicted and observed secondary structure of T4 phage lysozyme. Biochimica et Biophysica Acta (BBA)-Protein Struct. 405(2), 442–451 (1975)

    Google Scholar 

  9. Nazerian, P., et al.: Accuracy of abdominal ultrasound for the diagnosis of pneumoperitoneum in patients with acute abdominal pain: a pilot study. Critical Ultrasound J. 7(1), 1–7 (2015). https://doi.org/10.1186/s13089-015-0032-6

    Article  Google Scholar 

  10. Paster, S.B., Brogdon, B.G.: Roentgenographic diagnosis of pneumoperitoneum. JAMA 235(12), 1264–1267 (1976). https://doi.org/10.1001/jama.1976.03260380058035

    Article  Google Scholar 

  11. Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  12. Shi, B., Bai, X., Yao, C.: An end-to-end trainable neural network for image-based sequence recognition and its application to scene text recognition. IEEE Trans. Pattern Anal. Mach. Intell. 39, 2298–2304 (2016)

    Article  Google Scholar 

  13. Summers, R.M.: Progress in fully automated abdominal CT interpretation. Am. J. Roentgenol. 207(1), 67–79 (2016)

    Article  Google Scholar 

  14. Tompson, J.J., Jain, A., LeCun, Y., Bregler, C.: Joint training of a convolutional network and a graphical model for human pose estimation. In: Advances in Neural Information Processing Systems, pp. 1799–1807 (2014)

    Google Scholar 

  15. Yang, D., et al.: Automatic liver segmentation using an adversarial image-to-image network. In: Descoteaux, M., Maier-Hein, L., Franz, A., Jannin, P., Collins, D.L., Duchesne, S. (eds.) MICCAI 2017. LNCS, vol. 10435, pp. 507–515. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-66179-7_58

    Chapter  Google Scholar 

  16. Zhao, Z.Q., Zheng, P., Xu, S.T., Wu, X.: Object detection with deep learning: a review. IEEE Trans. Neural Netw. Learn. Syst. 1–21 (2019). https://doi.org/10.1109/TNNLS.2018.2876865

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Taubmann, O. et al. (2020). Automatic Detection of Free Intra-abdominal Air in Computed Tomography. In: Martel, A.L., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2020. MICCAI 2020. Lecture Notes in Computer Science(), vol 12262. Springer, Cham. https://doi.org/10.1007/978-3-030-59713-9_23

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  • DOI: https://doi.org/10.1007/978-3-030-59713-9_23

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-59712-2

  • Online ISBN: 978-3-030-59713-9

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