Abstract
The diagnostic quantification of thyroid gland, mostly based on its volume, is commonly done by ultrasound. Typically, three orthogonal length measurements on 2D images are used to estimate the thyroid volume from an ellipsoid approximation, which may vary substantially from its true shape. In this work, we propose a more accurate direct volume determination using 3D reconstructions from two freehand clips in transverse and sagittal directions. A deep learning based trajectory estimation on individual clips is followed by an image-based 3D model optimization of the overlapping transverse and sagittal image data. The image data and automatic thyroid segmentation are then reconstructed and compared in 3D space. The algorithm is tested on 200 pairs of sweeps, and shows that it can provide fully automated, but also more accurate and consistent volume estimations than the standard ellipsoid method, with a median volume error of \(11\%\).
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Brown, M.C., Spencer, R.: Thyroid gland volume estimated by use of ultrasound in addition to scintigraphy. Acta Radiol. Oncol. Radiat. Phys. Biol. 17(4), 337–341 (1978)
Chang, C.Y., Lei, Y.F., Tseng, C.H., Shih, S.R.: Thyroid segmentation and volume estimation in ultrasound images. IEEE Trans. Biomed. Eng. 57(6), 1348–1357 (2010)
Chen, J., You, H., Li, K.: A review of thyroid gland segmentation and thyroid nodule segmentation methods for medical ultrasound images. Comput. Methods Program Biomed. 185, 105329 (2020)
Karamalis, A., Wein, W., Kutter, O., Navab, N.: Fast hybrid freehand ultrasound volume reconstruction. In: Miga, M., Wong, I., Kenneth, H. (eds.) Proc. of the SPIE. 7261, 726114–726118 (2009)
Kumar, V., et al.: Automated segmentation of thyroid nodule, gland, and cystic components from ultrasound images using deep learning. IEEE Access 8, 63482–63496 (2020)
Lyshchik, A., Drozd, V., Reiners, C.: Accuracy of three-dimensional ultrasoundfor thyroid volume measurement in children and adolescents. Thyroid 14(2), 113–120 (2004). https://doi.org/10.1089/105072504322880346. pMID:15068625
O’Malley, S.M., Granada, J.F., Carlier, S., Naghavi, M., Kakadiaris, I.A.: Image-based gating of intravascular ultrasound pullback sequences. IEEE Trans. Inf. Technol. Biomed. 12(3), 299–306 (2008)
Prevost, R., et al.: 3D freehand ultrasound without external tracking using deep learning. Med. Image Anal. 48, 187–202 (2018)
Prevost, R., Salehi, M., Sprung, J., Ladikos, A., Bauer, R., Wein, W.: Deep learning for sensorless 3D freehand ultrasound imaging. In: Descoteaux, M., Maier-Hein, L., Franz, A., Jannin, P., Collins, D.L., Duchesne, S. (eds.) MICCAI 2017. LNCS, vol. 10434, pp. 628–636. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-66185-8_71
Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28
Shabana, W., Peeters, E., De Maeseneer, M.: Measuring thyroid gland volume: should we change the correction factor? Am. J. Roentgenol. 186(1), 234–236 (2006)
Wein, W., Khamene, A.: Image-based method for in-vivo freehand ultrasound calibration. In: SPIE Medical Imaging 2008, San Diego, (2008)
Wunderling, T., Golla, B., Poudel, P., Arens, C., Friebe, M., Hansen, C.: Comparison of thyroid segmentation techniques for 3D ultrasound. In: Styner, M.A., Angelini, E.D. (eds.) Medical Imaging 2017: Image Processing. International Society for Optics and Photonics, SPIE. 10133, 346–352 (2017) https://doi.org/10.1117/12.2254234
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Wein, W. et al. (2020). Three-Dimensional Thyroid Assessment from Untracked 2D Ultrasound Clips. In: Martel, A.L., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2020. MICCAI 2020. Lecture Notes in Computer Science(), vol 12263. Springer, Cham. https://doi.org/10.1007/978-3-030-59716-0_49
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DOI: https://doi.org/10.1007/978-3-030-59716-0_49
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