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\(\alpha \)-UNet++: A Data-Driven Neural Network Architecture for Medical Image Segmentation

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Domain Adaptation and Representation Transfer, and Distributed and Collaborative Learning (DART 2020, DCL 2020)

Abstract

UNet++, an encoder-decoder architecture constructed based on the famous UNet, has achieved state-of-the-art results on many medical image segmentation tasks. Despite improved performance, UNet++ introduces densely connected decoding blocks, some of which, however, are redundant for a specific task. In this paper, we propose \(\alpha \)-UNet++ that allows us to automatically identify and discard redundant decoding blocks without the loss of precision. To this end, we design an auxiliary indicator function layer to compress the network architecture via removing a decoding block, in which all individual responses are less than a given threshold \(\alpha \). We evaluated the segmentation architecture obtained respectively for liver segmentation and nuclei segmentation, denoted by UNet++\(^C\), against UNet and UNet++. Comparing to UNet++, our UNet++\(^C\) reduces the parameters by 18.89% in liver segmentation and 34.17% in nuclei segmentation, yielding an average improvement of IoU by 0.27% and 0.11% on two tasks. Our results suggest that the UNet++\(^C\) produced by the proposed \(\alpha \)-UNet++ not only improves the segmentation accuracy slightly but also reduces the model complexity considerably.

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Notes

  1. 1.

    https://decathlon-10.grand-challenge.org.

  2. 2.

    https://www.kaggle.com/c/data-science-bowl-2018/data.

References

  1. Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  2. Milletari, F., Navab, N., Ahmadi, S.A.: V-Net: fully convolutional neural networks for volumetric medical image segmentation. In: Proceedings of the Fourth International Conference on 3D Vision, pp. 565–571 (2016)

    Google Scholar 

  3. Shen, D., Wu, G., Suk, H.I.: Deep learning in medical image analysis. Ann. Rev. Biomed. Eng. 19, 221–248 (2017)

    Article  Google Scholar 

  4. Tajbakhsh, N., Jeyaseelan, L., Li, Q., Chiang, J., Wu, Z., Ding, X.: Embracing imperfect datasets: a review of deep learning solutions for medical image segmentation. arXiv preprint arXiv:1908.10454 (2019)

  5. Litjens, G., et al.: A survey on deep learning in medical image analysis. Med. Image Anal. 42, 60–88 (2017)

    Article  Google Scholar 

  6. Zhou, Z., Siddiquee, M.M.R., Tajbakhsh, N., Liang, J.: UNet++: redesigning skip connections to exploit multiscale features in image segmentation. IEEE Trans. Med. Imaging 39(6), 1856–1867 (2019)

    Article  Google Scholar 

  7. Huang, G., Liu, Z., Van Der Maaten, L., Weinberger, K.Q.: Densely connected convolutional networks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 4700–4708 (2017)

    Google Scholar 

  8. Li, X., Chen, H., Qi, X., Dou, Q., Fu, C.W., Heng, P.A.: H-DenseUNet: hybrid densely connected UNet for liver and tumor segmentation from CT volumes. IEEE Trans. Med. Imaging 37(12), 2663–2674 (2018)

    Article  Google Scholar 

  9. Drozdzal, M., Vorontsov, E., Chartrand, G., Kadoury, S., Pal, C.: The importance of skip connections in biomedical image segmentation. In: Carneiro, G., et al. (eds.) LABELS/DLMIA -2016. LNCS, vol. 10008, pp. 179–187. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46976-8_19

    Chapter  Google Scholar 

  10. Li, H., Kadav, A., Durdanovic, I., Samet, H., Graf, H.P.: Pruning filters for efficient convnets. arXiv preprint arXiv:1608.08710 (2016)

  11. Zhuo, H., Qian, X., Fu, Y., Yang, H., Xue, X.: SCSP: spectral clustering filter pruning with soft self-adaption manners. arXiv preprint arXiv:1806.05320 (2018)

  12. Suau, X., Zappella, L., Palakkode, V., Apostoloff, N.: Principal filter analysis for guided network compression. arXiv preprint arXiv:1807.10585 (2018)

  13. Yu, X., Yu, Z., Ramalingam, S.: Learning strict identity mappings in deep residual networks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 4432–4440 (2018)

    Google Scholar 

  14. Huang, Z., Wang, N.: Data-driven sparse structure selection for deep neural networks. In: Proceedings of the IEEE Conference on European Conference on Computer Vision, pp. 304–320 (2018)

    Google Scholar 

  15. He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 770–778 (2016)

    Google Scholar 

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Acknowledgment

This work was supported in part by the Science and Technology Innovation Committee of Shenzhen Municipality, China, under Grants JCYJ20180306171334997, and in part by the National Natural Science Foundation of China under Grants 61771397. We appreciate the efforts devoted by the organizers of the Medical Segmentation Decathlon (MSD) Challenge and 2018 Data Science Bowl Segmentation Challenge to collect and share the data for comparing medical image segmentation algorithms.

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Correspondence to Yong Xia .

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Chen, Y., Ma, B., Xia, Y. (2020). \(\alpha \)-UNet++: A Data-Driven Neural Network Architecture for Medical Image Segmentation. In: Albarqouni, S., et al. Domain Adaptation and Representation Transfer, and Distributed and Collaborative Learning. DART DCL 2020 2020. Lecture Notes in Computer Science(), vol 12444. Springer, Cham. https://doi.org/10.1007/978-3-030-60548-3_1

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  • DOI: https://doi.org/10.1007/978-3-030-60548-3_1

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