Abstract
Infection segmentation is essential for quantitative assessment in computer-aided management of COVID-19. However, clinical CT images are usually heterogeneous, which are reconstructed by different protocols with varying appearance and voxel spacing due to radiologist preference. Most existing infection segmentation models are only trained using specific types of CT images, which would undermine the performance when applied to other types of CT images. Therefore, it is highly desirable to construct a model that could be applied to heterogeneous CT images in the urgent COVID-19 applications. In this paper, we present a two-stage mapping-segmentation framework for delineating COVID-19 infections from CT images. To compensate for heterogeneity of CT images obtained from different imaging centers, we develop an image-level domain-adaptive process to transform all kinds of images into a target type, and then segment COVID-19 infections accordingly. Experiments show that the infection delineation performance based on our proposed method is superior to the model trained jointly using mixture of all types of images, and is also comparable to those models supervised by using only specific types of images (if applicable).
T. Li and Z. Wang—Contributed equally.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Wang, C., Horby, P.W., Hayden, F.G., Gao, G.F.: A novel coronavirus outbreak of global health concern. Lancet 395(10223), 470–473 (2020)
Ai, T et al.: Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases. Radiology, p. 200642 (2020)
Fang, Y., Zhang, H., Xie. J., Lin, M.: Sensitivity of chest CT for COVID-19: comparison to RT-PCR. Radiology, p. 200432 (2020)
Shan, F., Gao, Y., Wang, J.: Lung infection quantification of COVID-19 in CT images with deep learning (2020). arXiv preprint arXiv:2003.04655
Bernheim, A., Mei, X., Huang, M.: Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of infection. Radiology 26(1), 200463 (2020)
Dalrymple, N.C., Prasad, S.R., Freckleton, M.W.: Introduction to the language of three-dimensional imaging with multidetector CT. Radiographics 25(5), 1409–1428 (2005)
Zheng, C., Deng, X., Fu, Q.: Deep learning-based detection for COVID-19 from chest CT using weak label. medRxiv (2020)
Jin, S., Wang, B., Xu., H.: AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system in four weeks. medRxiv (2020)
Wang, X., Cai, Z., Gao, D.: Towards universal object detection by domain attention. In: CVPR (2019)
Liu, Y., et al.: Cross-modality knowledge transfer for prostate segmentation from CT scans. In: Wang, Q. (ed.) DART/MIL3ID -2019. LNCS, vol. 11795, pp. 63–71. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-33391-1_8
Liu, Q., Dou, Q., Yu, L., Heng, P.A.: MS-net: multi-site network for improving prostate segmentation with heterogeneous MRI data. IEEE Trans. Med. Imaging 39(9), 2713–2724 (2020)
Dar, S.U., Yurt, M., Karacan, L., Erdem, A.: Image synthesis in multi-contrast MRI with conditional generative adversarial networks. IEEE Trans. Med. Imaging 38(10), 2375–2388 (2020)
Mu, G., Lin, Z., Han, M.: Segmentation of kidney tumor by multi-resolution VB-nets (2019)
Orbes-Arteaga, M., et al.: Multi-domain adaptation in brain MRI through paired consistency and adversarial learning. In: Wang, Q. (ed.) DART/MIL3ID -2019. LNCS, vol. 11795, pp. 54–62. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-33391-1_7
Hoffman, J., Rodner, E., Donahue, J.: Efficient learning of domain-invariant image representations (2013). arXiv preprint arXiv:1301.3224
Yan, Y.H., Yang, Y.Z.: Image fusion based on principal component analysis in dual-tree complex wavelet transform domain. In: 2012 International Conference on Wavelet Active Media Technology and Information Processing (ICWAMTIP), pp. 70–73 (2012)
Goodfellow, L., Pouget-Abadie, J., Mirza, M.: Generative adversarial nets. In: Advances in neural information processing systems, pp. 2672–2680 (2014)
Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28
Milletari, F., Navab, N., Ahmad, S.A.: V-net: fully convolutional neural networks for volumetric medical image segmentation. In: Fourth International Conference on 3D vision (3DV) (2016)
Shi, F., Wang, J., Shi, J., Wu, Z.: Review of artificial intelligence techniques in imaging data acquisition, segmentation and diagnosis for COVID-19. IEEE Reviews in Biomedical Engineering, p. 1 (2016)
Author information
Authors and Affiliations
Corresponding authors
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this paper
Cite this paper
Li, T. et al. (2020). Two-Stage Mapping-Segmentation Framework for Delineating COVID-19 Infections from Heterogeneous CT Images. In: Petersen, J., et al. Thoracic Image Analysis. TIA 2020. Lecture Notes in Computer Science(), vol 12502. Springer, Cham. https://doi.org/10.1007/978-3-030-62469-9_1
Download citation
DOI: https://doi.org/10.1007/978-3-030-62469-9_1
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-62468-2
Online ISBN: 978-3-030-62469-9
eBook Packages: Computer ScienceComputer Science (R0)