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Two-Stage Mapping-Segmentation Framework for Delineating COVID-19 Infections from Heterogeneous CT Images

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Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 12502))

Abstract

Infection segmentation is essential for quantitative assessment in computer-aided management of COVID-19. However, clinical CT images are usually heterogeneous, which are reconstructed by different protocols with varying appearance and voxel spacing due to radiologist preference. Most existing infection segmentation models are only trained using specific types of CT images, which would undermine the performance when applied to other types of CT images. Therefore, it is highly desirable to construct a model that could be applied to heterogeneous CT images in the urgent COVID-19 applications. In this paper, we present a two-stage mapping-segmentation framework for delineating COVID-19 infections from CT images. To compensate for heterogeneity of CT images obtained from different imaging centers, we develop an image-level domain-adaptive process to transform all kinds of images into a target type, and then segment COVID-19 infections accordingly. Experiments show that the infection delineation performance based on our proposed method is superior to the model trained jointly using mixture of all types of images, and is also comparable to those models supervised by using only specific types of images (if applicable).

T. Li and Z. Wang—Contributed equally.

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References

  1. Wang, C., Horby, P.W., Hayden, F.G., Gao, G.F.: A novel coronavirus outbreak of global health concern. Lancet 395(10223), 470–473 (2020)

    Article  Google Scholar 

  2. Ai, T et al.: Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases. Radiology, p. 200642 (2020)

    Google Scholar 

  3. Fang, Y., Zhang, H., Xie. J., Lin, M.: Sensitivity of chest CT for COVID-19: comparison to RT-PCR. Radiology, p. 200432 (2020)

    Google Scholar 

  4. Shan, F., Gao, Y., Wang, J.: Lung infection quantification of COVID-19 in CT images with deep learning (2020). arXiv preprint arXiv:2003.04655

  5. Bernheim, A., Mei, X., Huang, M.: Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of infection. Radiology 26(1), 200463 (2020)

    Article  Google Scholar 

  6. Dalrymple, N.C., Prasad, S.R., Freckleton, M.W.: Introduction to the language of three-dimensional imaging with multidetector CT. Radiographics 25(5), 1409–1428 (2005)

    Article  Google Scholar 

  7. Zheng, C., Deng, X., Fu, Q.: Deep learning-based detection for COVID-19 from chest CT using weak label. medRxiv (2020)

    Google Scholar 

  8. Jin, S., Wang, B., Xu., H.: AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system in four weeks. medRxiv (2020)

    Google Scholar 

  9. Wang, X., Cai, Z., Gao, D.: Towards universal object detection by domain attention. In: CVPR (2019)

    Google Scholar 

  10. Liu, Y., et al.: Cross-modality knowledge transfer for prostate segmentation from CT scans. In: Wang, Q. (ed.) DART/MIL3ID -2019. LNCS, vol. 11795, pp. 63–71. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-33391-1_8

    Chapter  Google Scholar 

  11. Liu, Q., Dou, Q., Yu, L., Heng, P.A.: MS-net: multi-site network for improving prostate segmentation with heterogeneous MRI data. IEEE Trans. Med. Imaging 39(9), 2713–2724 (2020)

    Article  Google Scholar 

  12. Dar, S.U., Yurt, M., Karacan, L., Erdem, A.: Image synthesis in multi-contrast MRI with conditional generative adversarial networks. IEEE Trans. Med. Imaging 38(10), 2375–2388 (2020)

    Article  Google Scholar 

  13. Mu, G., Lin, Z., Han, M.: Segmentation of kidney tumor by multi-resolution VB-nets (2019)

    Google Scholar 

  14. Orbes-Arteaga, M., et al.: Multi-domain adaptation in brain MRI through paired consistency and adversarial learning. In: Wang, Q. (ed.) DART/MIL3ID -2019. LNCS, vol. 11795, pp. 54–62. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-33391-1_7

    Chapter  Google Scholar 

  15. Hoffman, J., Rodner, E., Donahue, J.: Efficient learning of domain-invariant image representations (2013). arXiv preprint arXiv:1301.3224

  16. Yan, Y.H., Yang, Y.Z.: Image fusion based on principal component analysis in dual-tree complex wavelet transform domain. In: 2012 International Conference on Wavelet Active Media Technology and Information Processing (ICWAMTIP), pp. 70–73 (2012)

    Google Scholar 

  17. Goodfellow, L., Pouget-Abadie, J., Mirza, M.: Generative adversarial nets. In: Advances in neural information processing systems, pp. 2672–2680 (2014)

    Google Scholar 

  18. Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  19. Milletari, F., Navab, N., Ahmad, S.A.: V-net: fully convolutional neural networks for volumetric medical image segmentation. In: Fourth International Conference on 3D vision (3DV) (2016)

    Google Scholar 

  20. Shi, F., Wang, J., Shi, J., Wu, Z.: Review of artificial intelligence techniques in imaging data acquisition, segmentation and diagnosis for COVID-19. IEEE Reviews in Biomedical Engineering, p. 1 (2016)

    Google Scholar 

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Correspondence to Qian Wang or Dinggang Shen .

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Li, T. et al. (2020). Two-Stage Mapping-Segmentation Framework for Delineating COVID-19 Infections from Heterogeneous CT Images. In: Petersen, J., et al. Thoracic Image Analysis. TIA 2020. Lecture Notes in Computer Science(), vol 12502. Springer, Cham. https://doi.org/10.1007/978-3-030-62469-9_1

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  • DOI: https://doi.org/10.1007/978-3-030-62469-9_1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-62468-2

  • Online ISBN: 978-3-030-62469-9

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