Abstract
Diagnosis of cervical dysplasia by visual inspection is a difficult problem. Most of the recent approaches use deep learning techniques to extract features and detect a region of interest (RoI) in the image. Such approaches can lead to loss of visual detail that appears weak and local within the cervical image. Also, it requires manual annotation to extract the RoI. Moreover, there are not many labeled data due to the medical image’s characteristics. To mitigate the problem, we present an approach that extracts global and local features in the image without manual annotation when there is a shortage of data. The proposed approach is applied to classify cervix cancer, and the results are demonstrated. First of all, we divide the cervix image into nine patches to extract visual features when high-resolution images are unavailable. Second, we generate a deep learning model sharing a weight between patches of the image by considering the patch-patch and patch-image relationship. We also apply an attention mechanism to the model to train the visual features of the image and show an interpretable result. Finally, we add a loss weighting inspired by the domain knowledge to the training process, which guides the learning better while preventing overfitting. The evaluation results indicate improvements over the state-of-the-art methods in sensitivity.
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Acknowledgments
We would like to express our gratitude to Dr. Mark Schiffman, Division of Cancer Epidemiology & Genetics, U.S. National Cancer Institute, for allowing us to use one of the NCI datasets. This research was supported by the MSIT (Ministry of Science, ICT), Korea, under the High-Potential Individuals Global Training Program) (2019-0-01599) supervised by the IITP (Institute for Information and Communications Technology Planning and Evaluation).
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Chae, J., Zhang, Y., Zimmermann, R., Kim, D., Kim, J. (2022). An Attention-Based Deep Learning Model with Interpretable Patch-Weight Sharing for Diagnosing Cervical Dysplasia. In: Arai, K. (eds) Intelligent Systems and Applications. IntelliSys 2021. Lecture Notes in Networks and Systems, vol 296. Springer, Cham. https://doi.org/10.1007/978-3-030-82199-9_43
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DOI: https://doi.org/10.1007/978-3-030-82199-9_43
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