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3-D Convolutional Neural Network Driven by Dimensionality Reduction for Hyperspectral Blood Cells Classification

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Abstract

Recent developments in convolutional neural network (CNN) led to an interest in the classification of blood cells hyperspectral images (HSI). However, traditional CNN algorithms cannot explore the intrinsic geometric structures of blood cells HSI, which may cause a limit in classification accuracy. To address this issue, this paper proposed a three-dimensional (3-D) convolutional neural network driven by dimensionality reduction termed 3DDRNet. 3DDRNet first designs a optimization criteria to compact intraclass neighbors and separate interclass samples in low-dimensional embedding space. Then, a 3-D convolutional neural network is used to extract spatial-spectral features for classification. Experimental results on the Bloodcell1-3 and Bloodcell2-2 datasets demonstrate that the proposed 3DDRNet can achieve better classification results than many state-of-the-art methods.

The GitHub Respository: https://github.com/jmjkx/MyConference.

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References

  1. Zhang, Q.M., et al.: Landscape and dynamics of single immune cells in hepatocellular carcinoma. Cell 179(4), 829–845 (2019)

    Article  Google Scholar 

  2. Sabatino, J.J., Probstel, A.K., Zamvil, S.S.: B cells in autoimmune and neurodegenerative central nervous system diseases. Nat. Rev. Neurosci. 20(12), 728–745 (2019)

    Article  Google Scholar 

  3. Henry, B.M., et al.: Red blood cell distribution width (RDW) predicts COVID-19 severity: a prospective, observational study from the cincinnati SARS-CoV-2 emergency department cohort. Diagnostics 10(9), 168 (2020)

    Article  Google Scholar 

  4. Nazlibilek, S., Karacor, D., Ercan, T., Sazli, M.H., Kalender, O., Ege, Y.: Automatic segmentation, counting, size determination and classification of white blood cells. Measurement 55, 58–65 (2014)

    Article  Google Scholar 

  5. Sato, T., Suzuki, R., Sunaga, R.: Maximum likelihood estimation of red blood cell aggregation degree based on calculation of local flow vector in blood circuit. Electr. Commun. Jpn. 101(12), 13–20 (2018)

    Article  Google Scholar 

  6. Mansourian, M., Kazemi, I., Kelishadi, R.: Pediatric metabolic syndrome and cell blood counts: bivariate bayesian modeling. J. Trop. Pediatr. 60(1), 61–67 (2014)

    Article  Google Scholar 

  7. Tai, W.L., Hu, R.M., Han, C.W.H., Chen, R.M., Tsai, J.J.P: Blood cell image classification based on hierarchical SVM. In: 2011 IEEE International Symposium on Multimedia, pp. 129–136. IEEE, Dana Point (2011)

    Google Scholar 

  8. Liang, G.B., Hong, H.C., Xie, W.F., Zheng, L.X.: Combining convolutional neural network with recursive neural network for blood cell image classification. IEEE Access 6, 36188–36197 (2018)

    Article  Google Scholar 

  9. Topol, E.J.: High-performance medicine: the convergence of human and artificial intelligence. Nat. Med. 25(1), 44–56 (2019)

    Article  Google Scholar 

  10. Apostolopoulos, I.D., Mpesiana, T.A.: Covid-19: automatic detection from X-ray images utilizing transfer learning with convolutional neural networks. Phys. Eng. Sci. Med. 43(2), 635–640 (2020). https://doi.org/10.1007/s13246-020-00865-4

    Article  Google Scholar 

  11. Dey, R., Lu, Z.J., Hong, Y.: Diagnostic classification of lung nodules using 3D neural networks. In: IEEE 15th International Symposium on Biomedical Imaging, pp. 774–778. IEEE, Washington DC (2018)

    Google Scholar 

  12. Kermany, D.S., et al.: Identifying medical diagnoses and treatable diseases by image-based deep learning. Cell 172(5), 1122–1131 (2018)

    Article  Google Scholar 

  13. Liskowski, P., Krawiec, K.: Segmenting retinal blood vessels with deep neural networks. IEEE Trans. Med. Imaging 35(11), 2369–2380 (2016)

    Article  Google Scholar 

  14. Khashman, A.: Investigation of different neural models for blood cell type identification. Neural Comput. Appl. 21(6), 1177–1183 (2012)

    Article  Google Scholar 

  15. Xu, K.J., Huang, H., Deng, P.F., Li, Y.: Deep feature aggregation framework driven by graph convolutional network for scene classification in remote sensing. IEEE Transactions on Neural Networks and Learning Systems (2021). https://doi.org/10.1109/TNNLS.2021.3071369

  16. Xu, K.J., Huang, H., Deng, P.F.: Remote sensing image scene classification based on global-local dual-branch structure model. IEEE Geoscience and Remote Sensing Letters (2021). https://doi.org/10.1109/LGRS.2021.3075712

  17. Khan, M.J., Khan, H.S., Yousaf, A., Khurshid, K., Abbas, A.: Modern trends in hyperspectral image analysis: a review. IEEE Access 6, 14118–14129 (2018)

    Article  Google Scholar 

  18. Lu, G.L., Fei, B.W.: Medical hyperspectral imaging: a review. J. Biomed. Opt. 19(1), 010901 (2014)

    Google Scholar 

  19. Jansen-Winkeln, B., et al.: Feedforward artificial neural network-based colorectal cancer detection using hyperspectral imaging: a step towards automatic optical biopsy. Cancers 13(5), 967 (2021)

    Article  Google Scholar 

  20. Li, X., Li, W., Xu, X.D., Hu, W.: Cell classification using convolutional neural networks in medical hyperspectral imagery. In: 2nd International Conference on Image. Vision and Computing, pp. 501–504. IEEE, Chengdu (2017)

    Google Scholar 

  21. Chang, L., Li, W., Li, Q.L.: Guided filter-based medical hyperspectral image restoration and cell classification. J. Med. Imaging Health Inform. 8(4), 826–835 (2018)

    Article  Google Scholar 

  22. Ran, Q., Chang, L., Li, W., Xu, X.F.: Spatial-spectral blood cell classification with microscopic hyperspectral imagery. In: Yu, J., Wang, Z., Hang, W., Zhao, B., Hou, X., Xie, M., Shimura, T. (eds.) AOPC 2017: Optical Spectroscopy and Imaging, LNCS, vol. 10461, UNSP 1046102. SPIE, Beijing (2017). https://doi.org/10.1117/12.2281268

  23. Pu, C.Y., Huang, H., Luo, L.Y.: Classification of hyperspectral image with attention mechanism-based dual-path convolutional network. IEEE Geosci. Remote Sens. Lett. 9, 1–5 (2021)

    Article  Google Scholar 

  24. Li, Z.Y., Huang, H., Duan, Y.L., Shi, G.Y.: DLPNet: a deep manifold network for feature extraction of hyperspectral imagery. Neural Netw. 129, 7–18 (2020)

    Article  Google Scholar 

  25. Huang, Q., Li, W., Zhang, B.C., Li, Q.L., Tao, R., Lovell, N.H.: Blood cell classification based on hyperspectral imaging with modulated gabor and CNN. IEEE J. Biomed. Health Inform. 24(1), 160–170 (2020)

    Article  Google Scholar 

  26. Wei, X.L., Li, W., Zhang, M.M., Li, Q.L.: Medical hyperspectral image classification based on end-to-end fusion deep neural network. IEEE Trans. Instrum. Meas. 68(11), 4481–4492 (2019)

    Article  Google Scholar 

  27. Shi, G.Y., Huang, H., Wang, L.H.: Unsupervised dimensionality reduction for hyperspectral imagery via local geometric structures feature learning. IEEE Geosci. Remote Sens. Lett. 17(8), 1425–1429 (2020)

    Article  Google Scholar 

  28. Duan, Y.L., Huang, H., Tang, Y.X.: Local constraint-based sparse manifold hypergraph learning for dimensionality reduction of hyperspectral image. IEEE Trans. Geosci. Remote Sens. 59(1), 613–628 (2021)

    Article  Google Scholar 

  29. Shi, G.Y., Luo, F.L., Tang, Y.M., Li, Y.: Dimensionality reduction of hyperspectral image based on local constrained manifold structure collaborative preserving embedding. Remote Sens. 13(7), 1363 (2021)

    Article  Google Scholar 

  30. Ravi, D., Fabelo, H., Callico, G.M., Yang, G.Z.: Manifold embedding and semantic segmentation for intraoperative guidance with hyperspectral brain imaging. IEEE Trans. Med. Imaging 19(1), 010901 (2014)

    Google Scholar 

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Acknowledgments

The authors would like to thank Professors Li Wei of Beijing Institute of Technology for providing us with the blood cells hyperspectral image. Thanks to the anonymous reviewers and the associate editor for their insightful comments and suggestions. This work was supported in part by the National Science Foundation of China under Grant 42071302, the Innovation Program for Chongqing Overseas Returnees under Grant cx2019144, and the Higher Education and Research Grants of NVIDIA.

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Yuan Li: Methodology, Validation, Data curation, Writing-review, Writing-original draft. Hong Huang: Supervision, Investigation, Methodology, Validation, Formal analysis, Writing-review & editing. Jian Wu: Methodology, Formal analysis, Validation, Writing-review. Yiming Tang: Formal analysis, Validation, Writing-review

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Correspondence to Hong Huang .

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The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Li, Y., Huang, H., Wu, J., Tang, Y. (2021). 3-D Convolutional Neural Network Driven by Dimensionality Reduction for Hyperspectral Blood Cells Classification. In: Peng, Y., Hu, SM., Gabbouj, M., Zhou, K., Elad, M., Xu, K. (eds) Image and Graphics. ICIG 2021. Lecture Notes in Computer Science(), vol 12889. Springer, Cham. https://doi.org/10.1007/978-3-030-87358-5_59

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  • DOI: https://doi.org/10.1007/978-3-030-87358-5_59

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-030-87358-5

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