Abstract
Bubbles in liquid have the advantages of controllability, compressibility and biocompatibility, so they are introduced into microfluidic system to drive the fluid and operate micro-objects including cells. In recent years, the acoustic and optothermal bubbles are the two most widely used and efficient bubbles in microfluidic devices. Therefore, the aim of this study is to review recent advances in acoustic bubble-based micromanipulators and optothermal bubble-based micromanipulators in microfluidic systems. The principles and applications of fluid control and micro-object operation of these two kinds of bubble-based manipulators are introduced and the prospects and challenges are discussed.
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Acknowledgement
This work is supported by the National Natural Science Foundation of China (Grant Nos. 91748212, U1613220, 91848201), and the CAS/SAFEA International Partnership Program for Creative Research Teams.
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Zhou, Y., Dai, L., Jiao, N., Liu, L. (2022). Bubble Based Micromanipulators in Microfluidics Systems: A Mini-review. In: Liu, H., et al. Intelligent Robotics and Applications. ICIRA 2022. Lecture Notes in Computer Science(), vol 13456. Springer, Cham. https://doi.org/10.1007/978-3-031-13822-5_51
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DOI: https://doi.org/10.1007/978-3-031-13822-5_51
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