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Intelligent Systems'2014 pp 657–668Cite as

Development of Generalized Net for Testing of Different Mathematical Models of E. coli Cultivation Process

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Part of the book series: Advances in Intelligent Systems and Computing ((AISC,volume 322))

Abstract

The present paper proposes a developed generalized net model that compares different mathematical models of the process of E. coli fed-batch cultivation. A system of four ordinary differential equations describes the main variables of the considered cultivation process, namely, biomass, substrate and acetate. For the purposes of model simulation, we use the software package GN Lite. The GN model compares the simulated performance of the proposed set of mathematical models and selects the best performing one one the basis of a predefined criterion. During the simulation, GN Lite calls the Matlab software environment to solve the process model, presented as a system of nonlinear differential equations, and plots the dynamics of the main process variables’ of the model that has been computed to perform best.

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Author information

Authors and Affiliations

  1. Faculty of Mathematics and Informatics, Sofia University St. Kliment Ohridski, 5 James Bourchier Str., Sofia, Bulgaria

    Dimitar Dimitrov

  2. Bioinformatics and Mathematical Modelling Department, IBPhBME – Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 105, 1113, Sofia, Bulgaria

    Olympia Roeva

Authors
  1. Dimitar Dimitrov
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  2. Olympia Roeva
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Corresponding author

Correspondence to Dimitar Dimitrov .

Editor information

Editors and Affiliations

  1. School of Computing and Communications, Lancaster University, Lancaster, United Kingdom

    P. Angelov

  2. Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria

    K.T. Atanassov

  3. Intelligent Systems Department, Bulgarian Academy of Sciences Inst. of Infor. & Communication Techn., Sofia, Bulgaria

    L. Doukovska

  4. Metalurgy, University of Chemical Technology and, Sofia, Bulgaria

    M. Hadjiski

  5. University of Library Studies and IT (ULSIT), Sofia, Bulgaria

    V. Jotsov

  6. Systems Research Institute, Polish Academy of Sciences, Warsaw, Poland

    J. Kacprzyk

  7. Knowledge Engineering and Discovery Research Institute, Auckland University of Technology, Auckland, New Zealand

    N. Kasabov

  8. Intelligent Systems Laboratory, Prof. Assen Zlatarov University Faculty of Technical Sciences, Bourgas, Bulgaria

    S. Sotirov

  9. Systems Research Institute, Polish Academy of Sciences, Warsaw, Poland

    E. Szmidt

  10. Systems Research Institute, Polish Academy of Sciences, Warsaw, Poland

    S. Zadrożny

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Dimitrov, D., Roeva, O. (2015). Development of Generalized Net for Testing of Different Mathematical Models of E. coli Cultivation Process. In: Angelov, P., et al. Intelligent Systems'2014. Advances in Intelligent Systems and Computing, vol 322. Springer, Cham. https://doi.org/10.1007/978-3-319-11313-5_58

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  • DOI: https://doi.org/10.1007/978-3-319-11313-5_58

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-11312-8

  • Online ISBN: 978-3-319-11313-5

  • eBook Packages: EngineeringEngineering (R0)

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