Skip to main content

Mining Longitudinal Epidemiological Data to Understand a Reversible Disorder

  • Conference paper

Part of the book series: Lecture Notes in Computer Science ((LNISA,volume 8819))

Abstract

Medical diagnostics are based on epidemiological findings about reliable predictive factors. In this work, we investigate how sequences of historical recordings of routinely measured assessments can contribute to better class separation. We show that predictive quality improves when considering old recordings, and that factors that contribute inadequately to class separation become more predictive when we exploit historical recordings of them. We report on our results for factors associated with a multifactorial disorder, hepatic steatosis, but our findings apply to further multifactorial outcomes.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Targher, G., Day, C.P., Bonora, E.: Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease. N. Eng. J. Med. 363(14), 1341–1350 (2010)

    Article  Google Scholar 

  2. Bedogni, G., Bellentani, S., ..., Castiglione, A., Tiribelli, C.: The Fatty Liver Index: a simple and accurate predictor of hepatic steatosis in the general population. BMC Gastroenterology 6(33), 7 (2006)

    Google Scholar 

  3. Völzke, H., Alte, D., ..., Biffar, R., John, U., Hoffmann, W.: Cohort profile: the Study of Health In Pomerania. Int. J. of Epidemiology 40(2), 294–307 (2011)

    Google Scholar 

  4. Hielscher, T., Spiliopoulou, M., Völzke, H., Kühn, J.P.: Using participant similarity for the classification of epidemiological data on hepatic steatosis. In: Proc. of the 27th IEEE Int. Symposium on Computer-Based Medical Systems (CBMS 2014), Mount Sinai, NY, IEEE (accepted March 2014)

    Google Scholar 

  5. Oh, E., Yoo, T., Park, E.C.: Diabetic retinopathy risk prediction for fundus examination using sparse learning: a cross-sectional study. BMC Med. Inf. and Decision Making 13(1), 1–14 (2013)

    Article  Google Scholar 

  6. Buczak, A., Koshute, P., Babin, S., Feighner, B., Lewis, S.: A data-driven epidemiological prediction method for dengue outbreaks using local and remote sensing data. BMC Med. Inf. and Decision Making 12(1), 1–20 (2012)

    Article  Google Scholar 

  7. Moskovitch, R., Shahar, Y.: Medical temporal-knowledge discovery via temporal abstraction. In: AMIA Annu. Symp. Proc., vol. 2009, p. 452. American Medical Informatics Association (2009)

    Google Scholar 

  8. Berlingerio, M., Bonchi, F., Giannotti, F., Turini, F.: Mining clinical data with a temporal dimension: A case study. In: IEEE 2007 Int. Conf. on Bioinf. and Biomed. (BIBM 2007), pp. 429–436 (November 2007)

    Google Scholar 

  9. Völzke, H., Craesmeyer, C., Nauck, M., ..., John, U., Baumeister, S.E., Ittermann, T.: Association of Socioeconomic Status with Iodine Supply and Thyroid Disorders in Northeast Germany . Thyroid 23(3), 346–353 (2013)

    Google Scholar 

  10. Haring, R., Wallaschofski, H., Nauck, M., Dörr, M., Baumeister, S.E., Völzke, H.: Ultrasonographic hepatic steatosis increased prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels. Hepatology 50, 1403–14011 (2009)

    Article  Google Scholar 

  11. Baumeister, S.E., Völzke, H., Marschall, P., ..., Schmidt, C., Flessa, S., Alte, D.: Impact of fatty liver disease on health care utilization and costs in a general population: A 5-year observation. Gastroenterology 134(1), 85–94 (2008)

    Google Scholar 

  12. Niemann, U., Völzke, H., Kühn, J.P., Spiliopoulou, M.: Learning and inspecting classification rules from longitudinal epidemiological data to identify predictive features on hepatic steatosis. Expert Systems with Applications (accepted February 2014)

    Google Scholar 

  13. Eick, C., Zeidat, N., Zhao, Z.: Supervised clustering - algorithms and benefits. In: 16th IEEE Int. Conf. on Tools with Artif. Int (ICTAI 2004), pp. 774–776. IEEE Computer Society, Boca Raton (2004)

    Google Scholar 

  14. Fayyad, U.M., Irani, K.B.: Multi-interval discretization of continuous-valued attributes for classification learning. In: Int. Joint Conf. on Artif. Inf (IJCAI 1993), pp. 1022–1029 (1993)

    Google Scholar 

  15. Ester, M., Kriegel, H.P., Sander, J., Xu, X.: A density-based algorithm for discovering clusters in large spatial databases with noise. In: Proc. of the 2nd Int. Conf. on Knowledge Discovery and Data Mining (KDD 1996), pp. 226–231. AAAI Press (1996)

    Google Scholar 

  16. Hall, M.A.: Correlation-based feature selection for discrete and numeric class machine learning. In: Proc. of 17th Int. Conf. on Machine Learning, pp. 359–366. Morgan Kaufmann, San Francisco (2000)

    Google Scholar 

  17. Wilson, D.R., Martinez, T.R.: Improved heterogeneous distance functions. J. Artif. Int. Res. 6(1), 1–34 (1997)

    MathSciNet  MATH  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer International Publishing Switzerland

About this paper

Cite this paper

Hielscher, T., Spiliopoulou, M., Völzke, H., Kühn, JP. (2014). Mining Longitudinal Epidemiological Data to Understand a Reversible Disorder. In: Blockeel, H., van Leeuwen, M., Vinciotti, V. (eds) Advances in Intelligent Data Analysis XIII. IDA 2014. Lecture Notes in Computer Science, vol 8819. Springer, Cham. https://doi.org/10.1007/978-3-319-12571-8_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-12571-8_11

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-12570-1

  • Online ISBN: 978-3-319-12571-8

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics