Abstract
Lung segmentation methods are important for automated lung image analysis tasks such as quantification of lung diseases. In this paper, we describe a method for segmentation of lungs with interstitial lung disease (ILD). In thoracic CT scans, such lungs are characterized by the presence of texture patterns like honeycombing, which makes lung segmentation difficult. We employ a 3D total variation L1 (TV-L1) based texture analysis approach to extract these patterns and attenuate the density of the corresponding voxels in the CT scan. The modified CT scan is then utilized as input to an existing 3D robust active shape model based lung segmentation method. The proposed method was evaluated on 77 CT scans of lungs with and without ILD. On cases with ILD, our method obtained an average volumetric overlap of 0.95±0.02, which was statistically significantly better than two other approaches. The TV-L1 texture analysis utilizes GPUs, making our method fast.
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References
Lynch, D.A., Travis, W.D., Müller, N.L., Galvin, J.R., Hansell, D.M., Grenier, P.A., King, T.E.: Idiopathic interstitial pneumonias: CT features. Radiology 236, 10–21 (2005)
Armato, S.G., Sensakovic, W.F.: Automated lung segmentation for thoracic CT: Impact on computer-aided diagnosis. Academic Radiology 11, 1011–1021 (2004)
Hu, S., Hoffman, E.A., Reinhardt, J.M.: Automatic lung segmentation for accurate quantitation of volumetric X-ray CT images. IEEE Transactions on Medical Imaging 20, 490–498 (2001)
Leader, J.K., Zheng, B., Rogers, R.M., Sciurba, F.C., Perez, A., Chapman, B.E., Patel, S., Fuhrman, C.R., Gur, D.: Automated lung segmentation in X-ray computed tomography: development and evaluation of a heuristic threshold-based scheme. Academic radiology 10, 1224–1236 (2003)
Kuhnigk, J.M., Dicken, V., Zidowitz, S., Bornemann, L., Kuemmerlen, B., Krass, S., Peitgen, H.O., Yuval, S., Jend, H.H., Rau, W.S., Achenbach, T.: New tools for computer assistance in thoracic CT. part 1. functional analysis of lungs, lung lobes, and bronchopulmonary segments. Radiographics 25, 525–536 (2005)
Uchiyama, Y., Katsuragawa, S., Abe, H., Shiraishi, J., Li, F., Li, Q., Zhang, C.T., Suzuki, K., Doi, K.: Quantitative computerized analysis of diffuse lung disease in high-resolution computed tomography. Medical Physics 30, 2440–2454 (2003)
Sluimer, I.C., Prokop, M., Hartmann, I., van Ginneken, B.: Automated classification of hyperlucency, fibrosis, ground glass, solid, and focal lesions in high-resolution CT of the lung. Medical Physics 33, 2610–2620 (2006)
Zavaletta, V.A., Bartholmai, B.J., Robb, R.A.: High resolution multidetector CT-aided tissue analysis and quantification of lung fibrosis. Academic Radiology 14, 772–787 (2007)
Zrimec, T., Busayarat, S.: A system for computer aided detection of diseases patterns in high resolution CT images of the lungs. In: Twentieth IEEE International Symposium on Computer-Based Medical Systems, CBMS 2007, pp. 41–46 (2007)
Shojaii, R., Alirezaie, J., Babyn, P.: Automatic segmentation of abnormal lung parenchyma utilizing wavelet transform. In: IEEE International Conference on Acoustics, Speech and Signal Processing, vol. 1, pp. 1217–1220 (2007)
Korfiatis, P., Kalogeropoulou, C., Karahaliou, A., Kazantzi, A., Skiadopoulos, S., Costaridou, L.: Texture classification-based segmentation of lung affected by interstitial pneumonia in high-resolution CT. Medical Physics 35, 5290–5302 (2008)
Wang, J., Li, F., Li, Q.: Automated segmentation of lungs with severe interstitial lung disease in CT. Medical physics 36, 4592–4599 (2009)
Kockelkorn, T., van Rikxoort, E., Grutters, J., Van Ginneken, B.: Interactive lung segmentation in CT scans with severe abnormalities. In: 2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, pp. 564–567 (2010)
Korfiatis, P., Kazantzi, A., Kalogeropoulou, C., Petsas, T., Costaridou, L.: Optimizing lung volume segmentation by texture classification. In: International Conference on Information Technology and Applications in Biomedicine, pp. 1–4 (2010)
Sun, S., Bauer, C., Beichel, R.: Automated 3D segmentation of lungs with lung cancer in CT data using a novel robust active shape model approach. IEEE Trans. Med. Imaging 31, 449–460 (2012)
Rudin, L.I., Osher, S., Fatemi, E.: Nonlinear total variation based noise removal algorithms. Physica D: Nonlinear Phenomena 60, 259–268 (1992)
Pock, T., Unger, M., Cremers, D., Bischof, H.: Fast and exact solution of total variation models on the GPU. In: IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops, CVPRW 2008, pp. 1–8 (2008)
Gill, G., Toews, M., Beichel, R.R.: Robust initialization of active shape models for lung segmentation in CT scans: A feature-based atlas approach. International Journal of Biomedical Imaging 2014, e479154 (2014)
Bauer, C., Pock, T., Bischof, H., Beichel, R.: Airway tree reconstruction based on tube detection. In: Proc. of the Second International Workshop on Pulmonary Image, pp. 203–213 (2009)
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Gill, G., Beichel, R.R. (2014). Segmentation of Lungs with Interstitial Lung Disease in CT Scans: A TV-L1 Based Texture Analysis Approach. In: Bebis, G., et al. Advances in Visual Computing. ISVC 2014. Lecture Notes in Computer Science, vol 8887. Springer, Cham. https://doi.org/10.1007/978-3-319-14249-4_48
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DOI: https://doi.org/10.1007/978-3-319-14249-4_48
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