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Biomedical Ontology Matching as a Service

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Smart Homes and Health Telematics (ICOST 2014)

Part of the book series: Lecture Notes in Computer Science ((LNISA,volume 8456))

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Abstract

Ontology matching is among the core techniques used for integration and interoperability resolution between biomedical systems. However, due to the excess usage and ever-evolving nature of biomedical data, ontologies are becoming large-scale, and complex; consequently, requiring scalable computational environments with performance and availability in mind. In this paper, we present a cloud-based ontology matching system for biomedical ontologies that provides ontology matching as a service. Our proposed system implements parallelism at various levels to improve the overall ontology matching performance especially for large-scale biomedical ontologies and incorporates third-party resources UMLS and Wordnet for comprehensive matched results. Matched results are delivered to the service consumer as bridge ontology and preserved in ubiquitous ontology repository for future request. We evaluate our system by consuming the matching service in an interoperability engine of a clinical decision support system (CDSS), which generates mapping requests for FMA and NCI biomedical ontologies.

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References

  1. López-Fernández, H., Reboiro-Jato, M., Glez-Pea, D., Aparicio, F., Gachet, D., Buenaga, M., Fdez-Riverola, F.: BioAnnote: a software platform for annotating biomedical documents with application in medical learning environments. Comput. Methods Programs Biomed. 111, 139–147 (2013)

    Article  Google Scholar 

  2. Cimino, J., Zhu, X.: IMIA Yearbook of Medical 1, 124–135 (2006)

    Google Scholar 

  3. Isern, D., Snchez, D., Moreno, A.: Ontology-driven execution of clinical guidelines. Comput. Methods Programs Biomed. 107, 122–139 (2012)

    Article  Google Scholar 

  4. De Potter, P., Cools, H., Depraetere, K., Mels, G., Debevere, P., De Roo, J., Huszka, C., Colaert, D., Mannens, E., Van de Walle, R.: Semantic patient information aggregation and medicinal decision support. Comput. Methods Programs Biomed. 2, 724–735 (2012)

    Article  Google Scholar 

  5. Gene Ontology Consortium: The Gene Ontology (GO) database and informatics resource. Nucleic Acid Res. (Database issue) 32, D258–D261 (2004)

    Article  Google Scholar 

  6. Golbeck, J., Fragoso, G., Hartel, F., Hendler, J., Oberthaler, J., Parsia, B.: The National Cancer Institute’s Thesaurus and ontology. Web Semant. Sci. Serv. Agents World Wide Web 1, 75–80 (2003)

    Article  Google Scholar 

  7. Rosse, C., Mejino, J.L.: A reference ontology for biomedical informatics. J. Biomed. Inform. 36, 478–500 (2003)

    Article  Google Scholar 

  8. Schulz, S., Cornet, R., Spackman, K.: Consolidating SNOMED CT’s ontological commitment. Appl. Ontol. 1, 1–11 (2011)

    Google Scholar 

  9. Smith, B., Ashburner, M., Rosse, C., Bard, J., Bug, W., Ceusters, W., Goldberg, L.J., Eilbeck, K., Ireland, A., Mungall, C.J., OBI Consortium, Leontis, N., Rocca-Serra, P., Ruttenberg, A., Sansone, S.A., Scheuermann, R.H., Shah, N., Whetzel P.L., Lewis, S.: The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration. Nat. Biotech 25, 1251–1255 (2007)

    Google Scholar 

  10. Jimnez-Ruiz, E., Meilicke, C., Cuenca Grau, B., Horrocks, I.: Evaluating mapping repair systems with large biomedical ontologies. In: 26th International Workshop on Description Logics. LNCS. Springer (2013)

    Google Scholar 

  11. Sun, X., Li, J.: pairheatmap: comparing expression profiles of gene groups in heatmaps. Comput. Methods Programs Biomed. 112, 599–606 (2013)

    Article  Google Scholar 

  12. Gennari, J.H., Silberfein, A.: Leveraging an alignment between two large ontologies: FMA and GO. In: Seventh International Protege Conference (2004)

    Google Scholar 

  13. Khan, W.A., Hussain, M., Afzal, M., Amin, M.B., Saleem, M.A., Lee, S.: Personalized-detailed clinical model for data interoperability among clinical standards. Telemed. e-Health 19, 632–642 (2013)

    Article  Google Scholar 

  14. Gross, A., Hartung, M., Kirsten, T., Rahm, E.: On matching large life science ontologies in parallel. In: Lambrix, P., Kemp, G. (eds.) DILS 2010. LNCS, vol. 6254, pp. 35–49. Springer, Heidelberg (2010)

    Chapter  Google Scholar 

  15. Schuyler, P.L., Hole, W.T., Tuttle, M.S., Sherertz, D.D.: The UMLS Metathesaurus: representing different views of biomedical concepts. Bull. Med. Libr. Assoc. 81, 217–222 (1993)

    Google Scholar 

  16. Princeton University, What is WordNet? (2013)

    Google Scholar 

  17. Shvaiko, P., Euzenat, J.: Ontology matching: state of the art and future challenges. IEEE Trans. Knowl. Data Eng. 25, 158–176 (2013)

    Article  Google Scholar 

  18. Lambrix, P., Tan, H.: SAMBO-A system for aligning and merging biomedical ontologies. Web Semant. 4, 196–206 (2006)

    Article  Google Scholar 

  19. National Center for Biotechnology Information, U.S. National Library of Medicine, PubMed (2013)

    Google Scholar 

  20. Jean-Mary, Y.R., Shironoshita, E.P., Kabuka, M.R.: Ontology matching with semantic verification. Web Semant. 7, 235–251 (2009)

    Article  Google Scholar 

  21. Ba, M., Diallo, G.: Large-scale biomedical ontology matching with ServOMap. IRBM 34, 56–59 (2011)

    Article  Google Scholar 

  22. Cruz, I.F., Antonelli, F.P., Stroe, C.: AgreementMaker: efficient matching for large real-world schemas and ontologies. Proc. VLDB Endow. 2, 1586–1589 (2009)

    Article  Google Scholar 

  23. Jiménez-Ruiz, E., Cuenca Grau, B.: LogMap: logic-based and scalable ontology matching. In: Aroyo, L., Welty, C., Alani, H., Taylor, J., Bernstein, A., Kagal, L., Noy, N., Blomqvist, E. (eds.) ISWC 2011, Part I. LNCS, vol. 7031, pp. 273–288. Springer, Heidelberg (2011)

    Chapter  Google Scholar 

  24. Kirsten, T., Gross, A., Hartung, M., Rahm, E.: GOMMA: a component-based infrastructure for managing and analyzing life science ontologies and their evolution. J. Biomed. Semant. 2, 6 (2011)

    Article  Google Scholar 

  25. Kirsten, T., Kolb, L., Hartung, M., Gross, A., Köpcke, H., Rahm, E.: Data partitioning for parallel entity matching. In: 8th International Workshop on Quality in Databases (2010)

    Google Scholar 

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Acknowledgment

This research was supported by Microsoft Research Asia, Beijing, China, under the research grant provided as MSRA Project Award 2013–2014 and MSIP(Ministry of Science, ICT&Future Planning), Korea, under IT/SW Creative research program supervised by the NIPA(National IT Industry Promotion Agency) (NIPA-2013-(H0503-13-1010).

This research was also supported by Microsoft Azure4Research Award 2013–2014.

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Correspondence to Muhammad Bilal Amin .

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Amin, M.B., Ahmad, M., Khan, W.A., Lee, S. (2015). Biomedical Ontology Matching as a Service. In: Bodine, C., Helal, S., Gu, T., Mokhtari, M. (eds) Smart Homes and Health Telematics. ICOST 2014. Lecture Notes in Computer Science(), vol 8456. Springer, Cham. https://doi.org/10.1007/978-3-319-14424-5_21

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  • DOI: https://doi.org/10.1007/978-3-319-14424-5_21

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-14423-8

  • Online ISBN: 978-3-319-14424-5

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