Abstract
Glaucoma, Pathological Myopia (PM), and Age-related Macular Degeneration (AMD) are three leading ocular diseases in the world. In this paper, we proposed a multiple ocular diseases diagnosis approach for above three diseases, with Entropic Graph regularized Probabilistic Multi-label learning (EGPM). The proposed EGPM exploits the correlations among these three diseases, and simultaneously classifying them for a given fundus image. The EGPM scheme contains two concatenating parts: (1) efficient graph construction based on k-Nearest-Neighbor (k-NN) search; (2) entropic multi-label learning based on Kullback-Leibler divergence. In addition, to capture the characteristics of these three leading ocular diseases, we explore the extractions of various effective low-level features, including Global Features, Grid-based Features, and Bag of Visual Words. Extensive experiments are conducted to validate the proposed EGPM framework on SiMES dataset. The results of Area Under Curve (AUC) in multiple ocular diseases classification outperform the state-of-the-art algorithms.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Quigley, H.A., Broman, A.T.: The number of people with glaucoma worldwide in 2010 and 2020. Br. J. Ophthalmol. 90(3), 262–267 (2006)
Xu, Y., Lin, S., Wong, D.W.K., Liu, J., Xu, D.: Efficient reconstruction-based optic cup localization for glaucoma screening. In: Mori, K., Sakuma, I., Sato, Y., Barillot, C., Navab, N. (eds.) MICCAI 2013, Part III. LNCS, vol. 8151, pp. 445–452. Springer, Heidelberg (2013)
Young, T.L., Ronan, S.M., Alvear, A.B., Wildenberg, S.C., Oetting, W.S., Atwood, L.D., Wilkin, D.J., King, R.A.: A second locus for familial high myopia maps to chromosome 12q. Am. J. Hum. Genet. 63(5), 1419–1424 (1998)
Xu, Y., Liu, J., Zhang, Z., Tan, N.M., Wong, D.W.K., Saw, S.M., Wong, T.Y.: Learn to recognize pathological myopia in fundus images using bag-of-feature and sparse learning approach. In: International Symposium on Biomedical Imaging, pp. 888–891 (2013)
Bressler, N.M., Bressler, S.B., Fine, S.L.: Age-related macular degeneration. Surv. Ophthalmol. 32(6), 375–413 (1988)
De Jong, P.T.: Age-related macular degeneration. N. Engl. J. Med. 355(14), 1474–1484 (2006)
Stricker, M., Orengo, M.: Similarity of color images. In: SPIE Storage and Retrieval for Image and Video Databases III (1995)
Avetisov, S.E., Erichev, V.P., Budzinskaia, M.V., Karpilova, M.A., Gurova, I.V., Shchegoleva, I.V., Chikun, E.A.: Age-related macular degeneration and glaucoma: intraocular pressure monitoring after intravitreal injections. Vestn. Oftalmol. 128(6), 3–5 (2012)
Pan, C.W., Cheung, C.Y., Aung, T., Cheung, C.M., Zheng, Y.F., Wu, R.Y., Mitchell, P., Lavanya, R., Baskaran, M., Wang, J.J., Wong, T.Y., Saw, S.M.: Differential associations of myopia with major age-related eye diseases: the Singapore Indian Eye Study. Ophthalmol 20(2), 284–291 (2013)
Subramanya, A., Bilmes, J.: Entropic graph regularization in non-parametric semi-supervised classification. In: NIPS (2009)
Foong, A.W.P., Saw, S.M., Loo, J.L., Shen, S., Loon, S.C., Rosman, M., Aung, T., Tan, D.T.H., Tai, E.S., Wong, T.Y.: Rationale and methodology for a population-based study of eye diseases in Malay people: the Singapore Malay eye study (SiMES). Ophthalmic Epidemiol. 14(1), 25–35 (2007)
Cheng, J., Wong, D.W.K., Cheng, X., Liu, J., Tan, N.M., Bhargava, M., Cheung, C.M.G., Wong, T.Y.: Early age-related macular degeneration detection by focal biologically inspired feature. In: ICIP (2012)
Shen, S.Y., Wong, T.Y., Foster, P.J., Loo, J.L., Rosman, M., Loon, S.C., Wong, W.L., Saw, S.M., Aung, T.: The prevalence and types of glaucoma in malay people: the singapore malay eye study. Invest. Ophthalmol. Vis. Sci. 49(9), 3846–3851 (2008)
Shapiro, L.G., Stockman, G.C.: Computer Vision. Prentice Hall, Englewood Cliffs (2003)
Qi, G., Hua, X., Rui, Y., Tang, J., Mei, T., Zhang, H.: Correlative multi-label video annotation. In: ACM Multimedia (2007)
Huang, J., Kumar, S., Mitra, M., Zhu, W.-J., Zabih, R.: Image indexing using color correlogram. In: IEEE Conference on Computer Vision and Pattern Recognition (1997)
Park, D.K., Jeon, Y.S., Won, C.S.: Efficient use of local edge histogram descriptor. In: ACM Multimedia (2000)
Wang, F., Zhang, C.: Label propagation through linear neighborhoods. In: ICML (2006)
Chen, G., Song, Y., Wang, F., Zhang, C.: Semi-supervised multi-label learning by solving a sylvester equation. In: SIAM International Conference on Data Mining (2008)
Chen, X., Mu, Y., Yan, S., Chua, T.-S.: Efficient large-scale image annotation by probabilistic collaborative multi-label propagation. In: ACM Multimedia (2010)
Wong, D.W.K., Liu, J., Cheng, X., Zhang, J., Yin, F., Bhargava, M., Cheung, C.M.G., Wong, T.Y.: THALIA - An automatic hierarchical analysis system to detect drusen lesion images for amd assessment. In: ISBI, pp. 884–887 (2013)
Manjunath, B.S., Ma, W.-Y.: Texture features for browsing and retrieval of image data. IEEE Trans. Pattern Anal. Mach. Intell. 18(8), 837–842 (1996)
Lowe, D.: Distinctive image features from scale-invariant keypoints. Int J. Comput. Vis. 2(60), 91–110 (2004)
Collobert, R., Sinz, F.H., Weston, J., Bottou, L.: Large scale transductive svms. J. Mach. Learn. Res. 7, 1687–1712 (2006)
Duda, R., Stork, D., Hart, P.: Pattern Classification. Wiley, New York (2000)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this paper
Cite this paper
Chen, X. et al. (2015). Multiple Ocular Diseases Classification with Graph Regularized Probabilistic Multi-label Learning. In: Cremers, D., Reid, I., Saito, H., Yang, MH. (eds) Computer Vision -- ACCV 2014. ACCV 2014. Lecture Notes in Computer Science(), vol 9006. Springer, Cham. https://doi.org/10.1007/978-3-319-16817-3_9
Download citation
DOI: https://doi.org/10.1007/978-3-319-16817-3_9
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-16816-6
Online ISBN: 978-3-319-16817-3
eBook Packages: Computer ScienceComputer Science (R0)