Abstract
In this study, we apply non-linear kernelized canonical correlation analysis (KCCA) as well as primal-dual sparse canonical correlation analysis (SCCA) to the discovery of correlations between sulphate reducing bacterial taxa and their geochemical environment in the deep biosphere. For visualization of canonical patterns, we demonstrate the applicability of the correlation plot technique on kernelized data. Finally, we provide an extension to the visual analysis by clustergrams. The presented framework and visualization tools enabled extraction of latent canonical correlation patterns between the salinity of the groundwater and the bacterial taxonomic orders Desulfobacterales, Desulfovibrionales and Clostridiales.
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References
Eisen, M.B., Spellman, P.T., Brown, P.O., Botstein, D.: Cluster analysis and display of genome-wide expression patterns. PNAS 95(25), 14863–14868 (1998)
González, I., Déjean, S., Martin, P.G., Gonçalves, O., Besse, P., Baccini, A.: Highlighting relationships between heterogeneous biological data through graphical displays based on regularized canonical correlation analysis. J. Biol. Syst. 17(02), 173–199 (2009)
González, I., Lê Cao, K.A., Davis, M.J., Déjean, S.: Visualising associations between paired omic data sets. BioData Min. 5(1), 1–23 (2012)
Hardoon, D., Szedmak, S., Shawe-Taylor, J.: Canonical correlation analysis: An overview with application to learning methods. Neural Comput. 16(12), 2639–2664 (2004)
Hardoon, D.R., Shawe-Taylor, J.: Sparse canonical correlation analysis. Mach. Learn. 83(3), 331–353 (2011)
Hotelling, H.: Relations between two sets of variates. Biometrika 28(3–4), 321–377 (1936)
Itävaara, M., Nyyssönen, M., Kapanen, A., Nousiainen, A., Ahonen, L., Kukkonen, I.: Characterization of bacterial diversity to a depth of 1500 m in the outokumpu deep borehole, fennoscandian shield. FEMS Microbiol. Ecol. 77(2), 295–309 (2011)
Kalogerakis, N., Arff, J., Banat, I.M., et al.: The role of environmental biotechnology in exploring, exploiting, monitoring, preserving, protecting and decontaminating the marine environment. New Biotechnol. 32(1), 157–167 (2015)
Lê Cao, K.A., Martin, P.G., Robert-Granié, C., Besse, P.: Sparse canonical methods for biological data integration: application to a cross-platform study. BMC Bioinformatics 10(1), 34 (2009)
Mevik, B.H., Wehrens, R.: The pls package: principal component and partial least squares regression in r. J. Stat. Softw. 18(2), 1–24 (2007)
Rajala, P., Carpén, L., Vepsäläinen, M., Raulio, M., Sohlberg, E., Bomberg, M.: Microbially induced corrosion of carbon steel in deep groundwater environment. Front. Microbiol. 6, 647 (2015)
Rousu, J., Agranoff, D.D., Sodeinde, O., Shawe-Taylor, J., Fernandez-Reyes, D.: Biomarker discovery by sparse canonical correlation analysis of complex clinical phenotypes of tuberculosis and malaria. PLoS Comput. Biol. 9(4), e1003018 (2013)
Waldron, P.J., Petsch, S.T., Martini, A.M., Nüsslein, K.: Salinity constraints on subsurface archaeal diversity and methanogenesis in sedimentary rock rich in organic matter. Appl. Environ. Microbiol. 73(13), 4171–4179 (2007)
Wang, X., Eijkemans, M.J., Wallinga, J., Biesbroek, G., Trzciński, K., Sanders, E.A., Bogaert, D.: Multivariate approach for studying interactions between environmental variables and microbial communities. PloS One 7(11), e50267 (2012)
Ye, R., Wright, A.L.: Multivariate analysis of chemical and microbial properties in histosols as influenced by land-use types. Soil and Tillage Res. 110(1), 94–100 (2010)
Zeng, J., Yang, L., Li, J., Liang, Y., Xiao, L., Jiang, L., Zhao, D.: Vertical distribution of bacterial community structure in the sediments of two eutrophic lakes revealed by denaturing gradient gel electrophoresis (dgge) and multivariate analysis techniques. World J. Microbiol. Biotechnol. 25(2), 225–233 (2009)
Acknowledgements
Microbiology data used in this article has been generated in several earlier projects. We acknowledge financial support from Finnish Research Programme on Nuclear Waste Management KYT2010 (2006–2010) (GEOMOL project) and KYT2014 (2011–2014) Geobioinfo and GEOMICRO projects. Finnish Academy is acknowledged for funding Deep Life project (2009–2014). The work by Viivi Uurtio has been supported in part by Helsinki Doctoral Network in Information and Communication Technology HICT.
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Uurtio, V., Bomberg, M., Nybo, K., Itävaara, M., Rousu, J. (2015). Canonical Correlation Methods for Exploring Microbe-Environment Interactions in Deep Subsurface. In: Japkowicz, N., Matwin, S. (eds) Discovery Science. DS 2015. Lecture Notes in Computer Science(), vol 9356. Springer, Cham. https://doi.org/10.1007/978-3-319-24282-8_25
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DOI: https://doi.org/10.1007/978-3-319-24282-8_25
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