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Outlier Detection in Cox Proportional Hazards Models Based on the Concordance c-Index

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Machine Learning, Optimization, and Big Data (MOD 2015)

Part of the book series: Lecture Notes in Computer Science ((LNISA,volume 9432))

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Abstract

Outliers can have extreme influence on data analysis and so their presence must be taken into account. We propose a method to perform outlier detection on multivariate survival datasets, named Dual Bootstrap Hypothesis Testing (DBHT). Experimental results show that DBHT is a competitive alternative to state-of-the-art methods and can be applied to clinical data.

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References

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Acknowledgments

Work supported by Fundação para a Ciência e a Tecnologia (FCT) under contracts LAETA (UID/EMS/50022/2013) and IT (UID/EEA/50008/2013), and by projects CancerSys (EXPL/EMS-SIS/1954/2013) and InteleGen (PTDC/DTP-FTO/1747/2012). SV acknowledges support by Program Investigador (IF/00653/2012) from FCT, co-funded by the European Social Fund through the Operational Program Human Potential.

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Correspondence to Susana Vinga .

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© 2015 Springer International Publishing Switzerland

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Pinto, J.D., Carvalho, A.M., Vinga, S. (2015). Outlier Detection in Cox Proportional Hazards Models Based on the Concordance c-Index. In: Pardalos, P., Pavone, M., Farinella, G., Cutello, V. (eds) Machine Learning, Optimization, and Big Data. MOD 2015. Lecture Notes in Computer Science(), vol 9432. Springer, Cham. https://doi.org/10.1007/978-3-319-27926-8_22

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  • DOI: https://doi.org/10.1007/978-3-319-27926-8_22

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-27925-1

  • Online ISBN: 978-3-319-27926-8

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