Abstract
Calculation and prediction of hydrodynamic properties of biological and synthetic macromolecules through computational approaches is a technique that has experimented a great advance in the last decades. However, most of the hydrodynamics software was designed decades ago and it is rather complex to use for less computer experienced users. With this objective in mind we have developed HYDROWEB, a tool that easily allows to work with hydrodynamic models of macromolecules and the calculation of their properties (using the softwares HYDROPRO, HYDRO++ and SIMUFLEX) and convenient visualization of its results. The tool can be accessed at http://bio-hpc.eu/software/hydroweb/.
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Acknowledgements
This work was supported by the Fundación Séneca–Agencia de Ciencia y Tecnología de la Región de Murcia under Projects 18946/JLI/13 and 19499/PI/14, by the Nils Coordinated Mobility under grant 012-ABEL-CM-2014A, in part financed by the European Regional Development Fund (ERDF), and by TETRACOM Technology Transfer in Computing Systems (funded by the European Union Commission Framework Programme 7 - Contract No. 609491), under Project ACDDTHPC. Powered@NLHPC: This research was partially supported by the supercomputing infrastructure of the NLHPC (ECM-02). The authors also thankfully acknowledge the computer resources and the technical support provided by the Plataforma Andaluza de Bioinformática of the University of Málaga. This work was partially supported by the computing facilities of Extremadura Research Centre for Advanced Technologies (CETACIEMAT), funded by the European Regional Development Fund (ERDF). CETACIEMAT belongs to CIEMAT and the Government of Spain.
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Pérez-Sánchez, H. et al. (2016). HYDROWEB, an Online Tool for the Calculation of Hydrodynamic Properties of Macromolecules. In: Ortuño, F., Rojas, I. (eds) Bioinformatics and Biomedical Engineering. IWBBIO 2016. Lecture Notes in Computer Science(), vol 9656. Springer, Cham. https://doi.org/10.1007/978-3-319-31744-1_8
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DOI: https://doi.org/10.1007/978-3-319-31744-1_8
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