Abstract
Magnetic resonance guided high intensity focused ultrasound (MRgHIFU) is a new therapy for treating malignant liver tissues. However, the motion of the ribs in the beam path may compromise an effective and safe treatment. Due to poor visibility of bones in MR and US liver images, tracking them in real time is currently not feasible. We propose a method for modeling and registration of the respiratory motion of the ribs. Moreover, we show that it is possible to predict the ribs’ motion based on a few tracked points in the liver. Our registration had a mean error of 1.06 mm for deep inhalations with an average motion of 2.71 mm. We developed subject-specific and population-based modeling methods, which recover 60 % and 40 % of the respiratory motion extracted through registration, respectively. To the best of our knowledge, this is the first time the ribs’ motion due to respiration has been directly studied during free breathing over a relatively long time (100 breathing cycles).
We acknowledge the grants n\(^o\) 270186 and n\(^o\) 611889 from the EU’s Seventh Framework Programme.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Gao, J., Volovick, A., Pekelny, Y., Huang, Z., Cochran, S., Melzer, A.: Focusing through the rib cage for MR-guided transcostal FUS. AIP Conf. Proc. 1481(1), 94–99 (2012)
Gray, H.: Anatomy of the human body. Bartleby.com, New York (2000). www.bartleby.com/107/
Ibanez, L., Schroeder, W., Ng, L., Cates, J.: The ITK Software Guide. Kitware Inc, second edn. ISBN 1-930934-15-7 (2005)
Jung, S.E., Cho, S.H., Jang, J.H., Han, J.Y.: High-intensity focused ultrasound ablation in hepatic and pancreatic cancer: Complications. Abdom. Imaging 36(2), 185–195 (2011)
Kennedy, J., Eberhart, R.: Particle swarm optimization. ICNN 4, 1942–1948 (1995)
McClelland, J., Hawkes, D., Schaeffter, T., King, A.: Respiratory motion models: A review. Med Image Anal. 17(1), 19–42 (2013)
Mohr, M., Abrams, E., Engel, C., Long, W.B., Bottlang, M.: Geometry of human ribs pertinent to orthopedic chest-wall reconstruction. J. Biomech. 40(6), 1310 (2007)
Samei, G., Székely, G., Tanner, C.: Detection and registration of ribs in MRI using geometric and appearance models. In: Golland, P., Hata, N., Barillot, C., Hornegger, J., Howe, R. (eds.) MICCAI 2014, Part I. LNCS, vol. 8673, pp. 706–713. Springer, Heidelberg (2014)
Samei, G., Tanner, C., Székely, G.: Predicting liver motion using exemplar models. In: Yoshida, H., Hawkes, D., Vannier, M.W. (eds.) MMCP 2012 and CCAAI 2012. LNCS, vol. 7601, pp. 147–157. Springer, Heidelberg (2012)
Tanner, C., Boye, D., Samei, G., Szekely, G.: Review on 4D models for organ motion compensation. Crit. Rev. Biomed. Eng. 40(2), 135 (2012)
Von Siebenthal, M., Székely, G., Gamper, U., Boesiger, P., Lomax, A., Cattin, P.: 4D MR imaging of respiratory organ motion and its variability. Phys. Med. Biol. 52, 1547 (2007)
Wilson, T., Rehder, K., Krayer, S., Hoffman, E., Whitney, C., Rodarte, J.: Geometry and respiratory displacement of human ribs. J. Appl. Physiol. 62(5), 1872 (1987)
Zhang, Z.: Iterative point matching for registration of free-form curves and surfaces. Int. J. Comput. Vis. 13(2), 119–152 (1994)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this paper
Cite this paper
Samei, G., Székely, G., Tanner, C. (2016). Prediction of Rib Motion During Free-Breathing from Liver Observations Using 4D MRI. In: Oyarzun Laura, C., et al. Clinical Image-Based Procedures. Translational Research in Medical Imaging. CLIP 2015. Lecture Notes in Computer Science(), vol 9401. Springer, Cham. https://doi.org/10.1007/978-3-319-31808-0_6
Download citation
DOI: https://doi.org/10.1007/978-3-319-31808-0_6
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-31807-3
Online ISBN: 978-3-319-31808-0
eBook Packages: Computer ScienceComputer Science (R0)