Skip to main content

Fully Convolutional Network for Liver Segmentation and Lesions Detection

  • Conference paper
  • First Online:
Book cover Deep Learning and Data Labeling for Medical Applications (DLMIA 2016, LABELS 2016)

Abstract

In this work we explore a fully convolutional network (FCN) for the task of liver segmentation and liver metastases detection in computed tomography (CT) examinations. FCN has proven to be a very powerful tool for semantic segmentation. We explore the FCN performance on a relatively small dataset and compare it to patch based CNN and sparsity based classification schemes. Our data contains CT examinations from 20 patients with overall 68 lesions and 43 livers marked in one slice and 20 different patients with a full 3D liver segmentation. We ran 3-fold cross-validation and results indicate superiority of the FCN over all other methods tested. Using our fully automatic algorithm we achieved true positive rate of 0.86 and 0.6 false positive per case which are very promising and clinically relevant results.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Ben-Cohen, A., Klang, E., Amitai, M., Greenspan, H.: Sparsity-based liver metastases detection using learned dictionaries. In: 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI), pp. 1195–1198 (2016)

    Google Scholar 

  2. Brosch, T., Yoo, Y., Tang, L.Y.W., Li, D.K.B., Traboulsee, A., Tam, R.: Deep convolutional encoder networks for multiple sclerosis lesion segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 3–11. Springer, Heidelberg (2015)

    Google Scholar 

  3. Deng, X., Du, G.: Editorial: 3D segmentation in the clinic: a grand challenge II-liver tumor segmentation. In: MICCAI Workshop (2008)

    Google Scholar 

  4. Heimann, T., et al.: Comparison and evaluation of methods for liver segmentation from CT datasets. IEEE Trans. Med. Imaging 28(8), 1251–1265 (2009)

    Article  Google Scholar 

  5. LeCun, Y., Bottou, L., Bengio, Y., Haffner, P.: Gradient-based learning applied to document recognition. Proc. IEEE 86, 2278–2324 (1998)

    Article  Google Scholar 

  6. Li, W., Jia, F., Hu, Q.: Automatic segmentation of liver tumor in CT images with deep convolutional neural networks. J. Comput. Commun. 3(11), 146 (2015)

    Article  Google Scholar 

  7. Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3431–3440 (2015)

    Google Scholar 

  8. Roth, H., Lu, L., Liu, J., Yao, J., Seff, A., Cherry, K., Kim, L., Summers, R.: Improving computer-aided detection using convolutional neural networks and random view aggregation. IEEE Trans. Med. Imaging, (2015, pre-print)

    Google Scholar 

  9. Rusko, L., Perenyi, A.: Automated liver lesion detection in CT images based on multi-level geometric features. Int. J. Comput. Assist. Radiol. Surg. 9(4), 577–593 (2014)

    Article  Google Scholar 

  10. Setio, A.A., Ciompi, F., Litjens, G., Gerke, P., Jacobs, C., van Riel, S., Wille, M.W., Naqibullah, M., Sanchez, C., van Ginneken, B.: Pulmonary nodule detection in CT images: false positive reduction using multi-view convolutional networks. IEEE Trans. Med. Imaging, (2016, pre-print)

    Google Scholar 

  11. Shimizu, A., et al.: Ensemble segmentation using AdaBoost with application to liver lesion extraction from a CT volume. In: Proceedings of Medical Imaging Computing Computer Assisted Intervention Workshop on 3D Segmentation in the Clinic: A Grand Challenge II, New York (2008)

    Google Scholar 

  12. Simonyan, K., Zisserman, A.: Very deep convolutional networks for large-scale image recognition. arXiv preprint arXiv:1409.1556 (2014)

  13. Vedaldi, A., Lenc, K.: MatConvNet: convolutional neural networks for matlab. In: Proceedings of the 23rd Annual ACM Conference on Multimedia Conference, pp. 689–692 (2015)

    Google Scholar 

  14. The World Health Report, World Health Organization (2014)

    Google Scholar 

Download references

Acknowledgment

Part of this work was funded by the INTEL Collaborative Research Institute for Computational Intelligence (ICRI-CI).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Avi Ben-Cohen .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing AG

About this paper

Cite this paper

Ben-Cohen, A., Diamant, I., Klang, E., Amitai, M., Greenspan, H. (2016). Fully Convolutional Network for Liver Segmentation and Lesions Detection. In: Carneiro, G., et al. Deep Learning and Data Labeling for Medical Applications. DLMIA LABELS 2016 2016. Lecture Notes in Computer Science(), vol 10008. Springer, Cham. https://doi.org/10.1007/978-3-319-46976-8_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-46976-8_9

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-46975-1

  • Online ISBN: 978-3-319-46976-8

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics