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Convegno Nazionale Sensori

CNS 2016: Sensors pp 267–275Cite as

Breath Analysis by a GC/MS Coupled to a Gas Sensor Detector

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Part of the book series: Lecture Notes in Electrical Engineering ((LNEE,volume 431))

Abstract

A peculiar experimental configuration of a gas chromatograph (GC) coupled, by a splitter, to two detectors, i.e. a mass spectrometer (MS) and a semiconducting gas sensor (SGS), operating in dual mode, was arranged. A suitable breath sampling system was used to sample the alveolar air volume in a bag from the air volume of a single expiration by discarding the dead volume. Breath volatiles (VOCs) were isolated and preconcentrated by solid-phase microextraction (SPME). Breath tests on alveolar air sampled by a sample of smokers volunteers were carried out. Statistical analysis techniques (descriptive statistics, Mann-Whitney test, PCA, Probit nonlinear regression model) applied to GC-MS data and sensor data showed good results in discriminating the subset of smokers sampled in resting condition (“blank” smokers) and after the action of smoking a cigarette.

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Author information

Authors and Affiliations

  1. National Research Council of Italy, Institute for Microelectronics and Microsystems (CNR-IMM), Via Monteroni, Campus Universitario, 73100, Lecce, Italy

    S. Capone, A. Forleo, F. Casino & P. Siciliano

  2. National Research Council of Italy, Istituto di Scienze delle Produzioni Alimentari, via Monteroni, Campus Universitario, 73100, Lecce, Italy

    M. Tufariello

Authors
  1. S. Capone
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  2. M. Tufariello
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  3. A. Forleo
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  4. F. Casino
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  5. P. Siciliano
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Corresponding author

Correspondence to S. Capone .

Editor information

Editors and Affiliations

  1. University of Catania, Catania, Italy

    Bruno Andò

  2. IFAC-CNR, Sesto Fiorentino, Italy

    Francesco Baldini

  3. University of Rome Tor Vergata, Rome, Italy

    Corrado Di Natale

  4. University of Florence, Sesto Fiorentino, Italy

    Giovanna Marrazza

  5. IMM-CNR, Lecce, Italy

    Pietro Siciliano

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Capone, S., Tufariello, M., Forleo, A., Casino, F., Siciliano, P. (2018). Breath Analysis by a GC/MS Coupled to a Gas Sensor Detector. In: Andò, B., Baldini, F., Di Natale, C., Marrazza, G., Siciliano, P. (eds) Sensors. CNS 2016. Lecture Notes in Electrical Engineering, vol 431. Springer, Cham. https://doi.org/10.1007/978-3-319-55077-0_35

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  • DOI: https://doi.org/10.1007/978-3-319-55077-0_35

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-55076-3

  • Online ISBN: 978-3-319-55077-0

  • eBook Packages: EngineeringEngineering (R0)

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