Abstract
Cerebral stroke is a cerebrovascular disease caused by an alteration of blood flow to the brain. Rodents are used to experiment with drugs provoking a stroke and studying the effects of different drugs as a measure of the relation of lesion volume to brain volume. Nowadays, clinicians are performing these experiments manually, leading to interhuman errors and not repeatability, of results, as well as being time-consuming tasks. This paper presents a methodology to automate this task, performing an automatic computation of the brain volume from the brain area for each slice of the rodent brain. Although in its initial state, results are very promising, and so work will follow in this way with the computation of lesion volume.
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Acknowledgments
This work has been subsidized by the Centro de Investigación en Tecnoloxías da Información (CiTIUS) from Universidade de Santiago de Compostela with financial support from the Consellería de Cultura, Educación e Ordenación Universitaria (accreditation 2016–2019, ED431G/08) and the European Regional Development Fund (ERDF) and partially supported by projects TIN2014-54583-C2-1-R and TIN2015-70308-REDT of the Spanish Ministerial Commission of Science and Technology (MINECO, Spain) and FEDER funds (EU).
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Camacho-Cañamón, J., Carreira, M.J., Gutiérrez, P.A., Iglesias-Rey, R. (2017). Estimating Rodent Brain Volume by a Deformable Contour Model. In: Valdés Hernández, M., González-Castro, V. (eds) Medical Image Understanding and Analysis. MIUA 2017. Communications in Computer and Information Science, vol 723. Springer, Cham. https://doi.org/10.1007/978-3-319-60964-5_60
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DOI: https://doi.org/10.1007/978-3-319-60964-5_60
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