Abstract
A three dimensional finite element model has been developed to investigate the sliding mechanics and compressibility of human lungs of seven lung cancer patients. The model consists of both lungs, tumor, and chest wall. The interaction between lungs and chest cavities is modeled using surface-based contact with coefficient of friction of 0, 0.1 and 0.2. Experimentally measured hyperelastic material properties of the lungs are applied in the model with different degrees of compressibility using Poisson’s ratio (ν) of 0.35, 0.4, 0.45 and 0.499. The analytical results are compared to actual measurements of the bifurcation of the vessels and bronchi in the lungs and tissues. The least absolute average error of 0.21(±0.04) cm is reached when frictionless contact surfaces with hyperelastic material and Poisson’s ratio of 0.35 and 0.4 are applied. The error slightly changes in contact models as the coefficient of friction and Poisson’s ratio increases. However, Poisson’s ratio has more effect in models without contact surfaces where the average error changes from 0.33(±0.11) cm to 0.26(±0.07) cm as the Poisson’s ratio increased from 0.35 to 0.499.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
McInerney, T., Tersopoulos, D.: Deformable models in medical image analysis: a survey. Med. Image Anal., 191–108 (1996)
Rietzel, E., Chen, G.T.Y., Choi, N.C., Willet, C.G.: Four dimensional image-based treatment planning: target, volume segmintation and dose calculation in the presence of respiratory motion. Int. J.Radiation Oncology Biol. Phys. 61, 1535–1550 (2005)
Brock, K.K.: Image registration in intensity-modulated radiation therapy, image-guided radiation therapy and stereotactic body radiation therapy. Front. Radiat. Ther. Oncol. 40, 94–115 (2007)
Yan, D., Jaffray, D.A., Wang, J.W.: A model to accumulate fractionated dose in a deforming organ. Int. J. Radiation Oncology Biol. Phys. 44, 665–675 (1999)
Bharath, A., Hirose, M., Hata, N., Warfield, S.K., Ferrant, M., Zou, K.H., Suarez-Santana, E., Ruis-Alzola, J., Kikinis, R., Jolesz, F.A., Tempany, C.M.C.: Evaluation of three-dimensional finite element-based deformable registration of pre- and intraoperative prostate imaging. Med. Phys. 28, 2551–2560 (2001)
Brock, K.K., Sharpe, M.B., Dawson, L.A., Kim, S.M., Jaffray, D.A.: Accuracy of finite element model-based multi-organ deformable image registration. Med. Phys. 32, 1647–1659 (2005)
Brock, K.K., Dawson, L.A., Sharpe, M.B., Moseley, D.J., Jaffray, D.A.: Feasibility of a novel deformable image registration technique to facilitate classification, targeting, and monitoring of tumor and normal tissue. Int. J. Radiation Oncology Biol. Phys. 64, 1245–1254 (2006)
Mead, J., Takishima, T., Leith, D.: Stress distribution in lungs: a model of pulmonary elasticity. J. Appl. Physiol. 28, 596–608 (1970)
West, J.B., Matthews, F.L.: Stresses, strains, and surface pressures in the lung caused by its weight. J. Appl. Physiol. 32, 332–345 (1972)
Sundaram, S.H., Feng, C.C.: Finite element analysis of the human thorax. J. Biomech. 10, 505–516 (1977)
Zeng, Y.J., Yager, D., Fung, Y.C.: Measurement of the mechanical properties of the human lung tissue. J. Biomech. Eng. 109, 169–174 (1987)
De Wilde, R., Clement, J., Hellemans, J.M., Decramer, M., Demedts, M., Boving, R., Van DeWoestijne, K.P.: Model of elasticity of the human lung. J. Appl. Physiol. 51, 254–261 (1981)
Villard, P., Beuve, M., Shariat, B., Baudet, V., Jaillet, F.: Simulation of lung behaviour with finite elements: Influence of bio-mechanical parameters. In: Proceedings of the 3rd International Conference on Medical Information Visualisation-BioMedical Visualisation, pp. 9–14 (2005)
Loring, S.E., Brown, R.E., Gouldstone, A., Butler, J.P.: Lubrication regimes in mesothelial sliding. Journal of Biomechanics 38, 2390–2396 (2005)
Zhang, T., Orton, N.P., Rockwell Mackie, T., Paliwal, B.R.: Technical note: A novel boundary condition using contact elements for finite element based deformable image registration. Med. Phys. 31, 2412–2415 (2004)
Al-Mayah, A., Moseley, J., Brock, K.K.: Contact surface and material nonlinearity modeling of human lungs. Phys. Med. Biol. 53, 305–317 (2008)
Widmaier, E.P., Raff, H., Strang, K.T.: Vander’s human physiology: the mechanisms of human body function, 10th edn. McGraw-Hill, New York (2006)
ABAQUS 6.7 Manual, Hibbitt, Karlsson & Sorensen, Inc.
Author information
Authors and Affiliations
Editor information
Rights and permissions
Copyright information
© 2008 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Al-Mayah, A., Moseley, J., Velec, M., Brock, K. (2008). Effect of Friction and Material Compressibility on Deformable Modeling of Human Lung. In: Bello, F., Edwards, P.J.E. (eds) Biomedical Simulation. ISBMS 2008. Lecture Notes in Computer Science, vol 5104. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-70521-5_11
Download citation
DOI: https://doi.org/10.1007/978-3-540-70521-5_11
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-70520-8
Online ISBN: 978-3-540-70521-5
eBook Packages: Computer ScienceComputer Science (R0)