Abstract
In this paper, we study the mechanics of the brain during closed head impact via numerical simulation. We propose a mathematical model of the human head, which consists of three layers: the rigid skull, the cerebrospinal fluid and the solid brain. The fluid behavior is governed by the Navier-Stokes equations, and the fluid and solid interact together according to the laws of mechanics. Numerical simulations are then performed on this model to simulate accident scenarios. Several theories have been proposed to explain whether the ensuing brain injury is dominantly located at the site of impact (coup injury) or at the site opposite to it (contrecoup injury). In particular, we investigate the positive pressure theory, the negative pressure theory, and the cerebrospinal fluid theory. The results of our numerical simulations together with pathological findings show that no one theory can explain the mechanics of the brain during the different types of accidents. We therefore highlight the accident scenarios under which each theory presents a consistent explanation of brain mechanics.
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References
Lindenberg, R., Freytag, E.: The mechanism of cerebral contusions. AMA Archives of Pathology 69, 440–469 (1960)
Denny-Brown, D., Russell, W.R.: Experimental cerebral concussion. Brain 64, 95–164 (1941)
Denny-Brown, D.: Cerebral concussion. Neurological Unit, Boston City Hospital, and the Department of Neurology, Harvard Medical School
Gurdjian, E., Gurdjian, E.S.: Cerebral contusions: Re-evaluation of the mechanism of their development. The Journal of Trauma 16, 35–51 (1976)
Russell, W.: Cerebral involvement in head injury. Brain 55, 549 (1932)
Lindenberg, R.: Trauma of meninges and brain. In: Minckler, J. (ed.) Pathology of the nervous system. McGraw-Hill, New York (1971)
Dawson, S.L., Hirsh, C.S.: The contrecoup phenomenon, reappraisal of a classical problem. Human Pathology 11, 155–166 (1980)
Gross, A.: A new theory on the dynamics of brain concussion and brain injury. Journal of Neurosurgery 15, 548 (1958)
Drew, L.B., Drew, W.E.: The contrecoup-coup phenomenon-a new understanding of the mechanism of closed head injury. Neurocritical Care 4(3), 385–390 (2004)
for Neuro Skills, C, http://www.neuroskills.com/edu/ceuoverview5.shtml
Brands, D.: Predicting brain mechanics during closed head impact. PhD thesis, Eidhoven University of Technology (2002)
Belingardi, G., Chiandussi, G., Gaviglio, I.: Development and validation of a new finite element model of human head. Technical report, Politecnio di Torino, Dipartimento di Meccanica, Italy (2005)
Chu, C.S., Lin, M.S., Huang, H.M., Lee, M.C.: Finite element analysis of cerebral contusion. Journal of Biomechanics 27(2), 187–194 (1994)
Chu, Y., Bottlang, M.: Finite element analysis of traumatic brain injury. In: Legacy Clinical Research and Technology Center, Portland, OR,
Engin, A.E.: The axisymmetric response of a fluid-filled spherical shell to a local radial impulse–a model for head injury. Journal of Biomechanics 2, 325–341 (1969)
Kenner, V., Goldsmith, W.: Impact on a simple physical model of the head. Journal of Biomechanics 6, 1–11 (1973)
Cotter, C.S., Szczyrba, P.S.I.: A viscoelastic fluid model for brain injuries. International Journal for numerical methods in fluids 40, 303–311 (2002)
Szczyrba, I., Burtscher, M.: On the role of ventricles in diffuse axonal injuries. In: Summer Bioengineering Conference (2003)
Landau, L., Lifshitz, E.: Fluid Mechanics. Pergamon Press, Oxford (1987)
Osher, S., Sethian, J.A.: Fronts propagating with curvature-dependent speed:algorithms based on hamilton-jacobi formulation. Journal of Computational Physics 79, 12–49 (1988)
Sethian, J.A.: Level Set Methods and Fast Marching Methods, 2nd edn. Cambridge University Press, Cambridge (1999)
Osher, S., Fedkiw, R.: Level Set Methods and Dynamic Implicit Surfaces. Springer, Heidelberg (2003)
Tome, M.F., McKee, S.: Gensmac: A computational marker and cell method for free surface flows in general domains. Journal of Computational Physics 110, 171–186 (1994)
Guyton, A., Hall, J.: Textbook of Medical Physiology, 11th edn. Elsevier Sauders, Amsterdam (2006)
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Halabieh, O., Wan, J.W.L. (2008). Simulating Mechanism of Brain Injury During Closed Head Impact. In: Bello, F., Edwards, P.J.E. (eds) Biomedical Simulation. ISBMS 2008. Lecture Notes in Computer Science, vol 5104. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-70521-5_12
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DOI: https://doi.org/10.1007/978-3-540-70521-5_12
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-70520-8
Online ISBN: 978-3-540-70521-5
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