Abstract
We report on the design of a dual-energy X-ray absorptiometry (DXA) method applied to Hologic Selenia digital mammography systems. The aim of the project is to quantify breast composition without thickness assumptions. The method is intended to be applied to standard mammography views as well as ex vivo breast samples. We established the calibration and accuracy using novel calibration phantoms. In this paper, we present our method and preliminary results using an excised whole breast sample. Results showed an average accuracy on the measurements to be less than 3% in the determination of the percent density of the breast phantoms. The chemical analysis of the excised breast and the DXA results agreed within 2%.
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References
Boyd, N.F., Byng, J.W., Jong, R.A., Fishell, E.K., Little, L.E., Miller, A.B., Lockwood, G.A., Tritchler, D.L., Yaffe, M.J.: Quantitative Classification of Mammographic Densities and Breast-Cancer Risk - Results from the Canadian National Breast Screening Study. Journal of the National Cancer Institute 87(9), 670–675 (1995)
Byrne, C., Schairer, C., Wolfe, J., Parekh, N., Salane, M., Brinton, L.A., Hoover, R., Haile, R.: Mammographic Features and Breast-Cancer Risk - Effects with Time, Age, and Menopause Status. Journal of the National Cancer Institute 87(21), 1622–1629 (1995)
Shepherd, J.A., Herve, L., Landau, J., Fan, B., Kerlikowske, K., Cummings, S.R.: Clinical comparison of a novel breast DXA technique to mammographic density. Medical Physics 33(5), 1490–1498 (2006)
Shepherd, J.A., Kerlikowske, K.M., Smith-Bindman, R., Genant, H.K., Cummings, S.R.: Measurement of breast density with dual x-ray absorptiometry: Feasibility. Radiology 223(2), 554–557 (2002)
Lehmann, L.A., Alvarez, R.E., Macovski, A., Brody, W.R., Pelc, N.J., Riederer, S.J., Hall, A.L.: Generalized Image Combinations in Dual Kvp Digital Radiography. Medical Physics 8(5), 659–667 (1981)
Hammerstein, G.R., Miller, D.W., White, D.R., Masterson, M.E., Woodard, H.Q., Laughlin, J.S.: Absorbed radiation dose in mammography. Radiology 130(2), 485–491 (1979)
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© 2008 Springer-Verlag Berlin Heidelberg
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Laidevant, A., Malkov, S., Au, A., Shepherd, J. (2008). Dual-Energy X-Ray Absorptiometry Method Using a Full Field Digital Mammography System. In: Krupinski, E.A. (eds) Digital Mammography. IWDM 2008. Lecture Notes in Computer Science, vol 5116. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-70538-3_16
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DOI: https://doi.org/10.1007/978-3-540-70538-3_16
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-70537-6
Online ISBN: 978-3-540-70538-3
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