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Computational Intelligence in Biomedicine and Bioinformatics pp 397–421Cite as

From Biomedical Literature to Knowledge: Mining Protein-Protein Interactions

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Part of the book series: Studies in Computational Intelligence ((SCI,volume 151))

Summary

To date, more than 16 million citations of published articles in biomedical domain are available in the MEDLINE database. These articles describe the new discoveries which accompany a tremendous development in biomedicine during the last decade. It is crucial for biomedical researchers to retrieve and mine some specific knowledge from the huge quantity of published articles with high efficiency. Researchers have been engaged in the development of text mining tools to find knowledge such as protein-protein interactions, which are most relevant and useful for specific analysis tasks. This chapter provides a road map to the various information extraction methods in biomedical domain, such as protein name recognition and discovery of protein-protein interactions. Disciplines involved in analyzing and processing unstructured-text are summarized. Current work in biomedical information extracting is categorized. Challenges in the field are also presented and possible solutions are discussed.

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Authors and Affiliations

  1. Informatics Research Centre, The University of Reading, Reading, RG6 6BX, UK

    Deyu Zhou & Yulan He

  2. School of Computer Engineering, Nanyang Technological University, Singapore, 639798

    Chee Keong Kwoh

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  1. Deyu Zhou
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  2. Yulan He
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Editors and Affiliations

  1. Department of Biology, Emory University, 1510 Clifton Rd.NE, 30322, Atlanta, Georgia, USA

    Tomasz G. Smolinski

  2. Department of Computer Science, University of Arkansas at Little Rock, 2801 S.University Ave., 72204, Little Rock, Arkansas, USA

    Mariofanna G. Milanova

  3. Department of Quantitative Methods and Information Systems College of Business and Administration, Kuwait University, P.O. Box 5486, 13055, Safat, Kuwait

    Aboul-Ella Hassanien

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Zhou, D., He, Y., Kwoh, C.K. (2008). From Biomedical Literature to Knowledge: Mining Protein-Protein Interactions. In: Smolinski, T.G., Milanova, M.G., Hassanien, AE. (eds) Computational Intelligence in Biomedicine and Bioinformatics. Studies in Computational Intelligence, vol 151. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-70778-3_17

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