Abstract
We developed an infant circulation model which incorporates an accurate myocardial cell model including a beta adrenergic system. The beta adrenergic system is essential for the response reproduction of the baroreflex control system. The proposed model was constructed by modifying the parameters of a human adult circulation model with the aid of a guinea pig myocardial cell model, whose baseline heart rate is close to that of an infant. The presented model is in good agreement with results obtained in physiological experiments.
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Nobuaki, Y., Amano, A., Shimayoshi, T., Lu, J., Shim, E.B., Matsuda, T. (2007). A Model for Simulation of Infant Cardiovascular Response to Orthostatic Stress. In: Sachse, F.B., Seemann, G. (eds) Functional Imaging and Modeling of the Heart. FIMH 2007. Lecture Notes in Computer Science, vol 4466. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72907-5_20
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DOI: https://doi.org/10.1007/978-3-540-72907-5_20
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-72906-8
Online ISBN: 978-3-540-72907-5
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