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A Recursive Anisotropic Fast Marching Approach to Reaction Diffusion Equation: Application to Tumor Growth Modeling

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Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 4584))

Abstract

Bridging the gap between clinical applications and mathematical models is one of the new challenges of medical image analysis. In this paper, we propose an efficient and accurate algorithm to solve anisotropic Eikonal equations, in order to link biological models using reaction-diffusion equations to clinical observations, such as medical images. The example application we use to demonstrate our methodology is tumor growth modeling. We simulate the motion of the tumor front visible in images and give preliminary results by solving the derived anisotropic Eikonal equation with the recursive fast marching algorithm.

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References

  • Aronson, D., Weinberger, H.: Multidimensional nonlinear diffusion arising in population genetics. Advances in Mathematics 30 (1978)

    Google Scholar 

  • Ebert, U.: W.S.: Front propagation into unstable states: universal algebraic convergence towards uniformly translating pulled fronts. Physica D: Nonlinear Phenomena 146 (2000)

    Google Scholar 

  • Tovi, M.: Mr imaging in cerebral gliomas analysis of tumour tissue components. Acta Radiol. Suppl. (1993)

    Google Scholar 

  • Sethian, J., Vladimirsky, A.: Ordered upwind methods for static hamilton-jacobi equations: theory and algorithms. SIAM J. Numer. Anal. 41 (2003)

    Google Scholar 

  • Kao, C., Osher, S., Tsai, Y.: Fast sweeping methods for static hamilton-jacobi equations. SIAM J. Numer. Anal. 42 (2005)

    Google Scholar 

  • Qian, J., Zhang, Y., Zhao, H.: A fast sweeping method for static convex hamilton-jacobi equations. UCLA Comp. and App. Math. Reports, 06-37 (2006)

    Google Scholar 

  • Kevorkian, J.: Partial differential equations: Analytical solution techniques. Springer, Heidelberg (2000)

    MATH  Google Scholar 

  • Sethian, J.: Level set methods and fast marching methods: Evolving interfaces in computational geometry, fluid mechanics, computer vision, and materials science. Cambridge University Press, Cambridge (1999)

    MATH  Google Scholar 

  • Qian, J., Symes, W.: Paraxial eikonal solvers for anisotropic quasi-p travel times. J. Comp. Physics, 173 (2001)

    Google Scholar 

  • Keener, J., Sneyd, J.: Mathematical physiology. Springer, Heidelberg (1998)

    MATH  Google Scholar 

  • Murray, J.: Mathematical Biology. Springer, Heidelberg (2002)

    MATH  Google Scholar 

  • Maini, P., McElwain, D., Leavesley, D.: Traveling wave model to interpret a wound-healing cell migration assay for human peritoneal mesothelial cells. Tissue Eng. 10 (2004)

    Google Scholar 

  • Bramson, M.: Convergence of solutions of the kolmogoroff equations to traveling waves. Mem. Am. Math. Soc (1983)

    Google Scholar 

  • Cristini, V., Lowengrub, J., Nie, Q.: Nonlinear simulation of tumor growth. Journal of Math. Biol. 46 (2003)

    Google Scholar 

  • Swanson, K., Alvord, E., Murray, J.: Virtual brain tumours (gliomas) enhance the reality of medical imaging and highlight inadequacies of current therapy. British Journal of Cancer, 86 (2002)

    Google Scholar 

  • Clatz, O., Sermesant, M., Bondiau, P., Delingette, H., Warfield, S., Malandain, G., Ayache, N.: Realistic simulation of the 3d growth of brain tumors in mr images coupling diffusion with biomechanical deformation. IEEE T.M.I. 24(10) (2005)

    Google Scholar 

  • Giese, A., Kluwe, L., Laube, B., Meissner, H., Berens, M., Westphal, M.: Migration of human glioma cells on myelin. Neurosurgery, 38(4) (1996)

    Google Scholar 

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Nico Karssemeijer Boudewijn Lelieveldt

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© 2007 Springer Berlin Heidelberg

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Konukoglu, E., Sermesant, M., Clatz, O., Peyrat, JM., Delingette, H., Ayache, N. (2007). A Recursive Anisotropic Fast Marching Approach to Reaction Diffusion Equation: Application to Tumor Growth Modeling. In: Karssemeijer, N., Lelieveldt, B. (eds) Information Processing in Medical Imaging. IPMI 2007. Lecture Notes in Computer Science, vol 4584. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-73273-0_57

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  • DOI: https://doi.org/10.1007/978-3-540-73273-0_57

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-73272-3

  • Online ISBN: 978-3-540-73273-0

  • eBook Packages: Computer ScienceComputer Science (R0)

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