Skip to main content

Integration of Brain-Gene Ontology and Simulation Systems for Learning, Modelling and Discovery

  • Chapter
Computational Intelligence in Medical Informatics

Part of the book series: Studies in Computational Intelligence ((SCI,volume 85))

  • 627 Accesses

This chapter discusses and presents some preliminary results on the Brain-Gene Ontology project that is concerned with the collection, presentation and use of knowledge in the form of ontology equipped with the Knowledge Discovery means of Computational Intelligence. Brain-Gene Ontology system thus includes various concepts, facts, data, graphs, visualizations, animations, and other information forms, related to brain functions, brain diseases, their genetic basis and the relationship between all of them, and various software simulators. The first version of the Brain-Gene Ontology has been completed as an evolving hierarchical structure in the Protégé ontology building environment endowed with plugins into the CI knowledge discovery packages like NeuCom, Weka, Siftware, and others.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. The National Center for Biotechnology Information (2007) The Nervous system. In: Genes and disease http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=gnd.chapter.75&ref=toc

  2. Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, et al. (2000) Gene ontology: tool for the unification of biology. Nature Genetics 25:25–29

    Article  Google Scholar 

  3. Benuskova L, Jain V, Wysoski SG, Kasabov N (2006) Computational neurogenetic modelling: a pathway to new discoveries in genetic neuroscience. Intl. J. Neural Systems 16:215–227

    Article  Google Scholar 

  4. Benuskova L, Kasabov N (2007) Computational neurogenetic modeling. Springer, New York

    Google Scholar 

  5. Chandrasekaran B, Josephson JR, Benjamins VR (1999) What are ontologies, and why do we need them? Intelligent Systems and Their Applications 14:20–26

    Article  Google Scholar 

  6. Fensel D (2004) Ontologies: a silver bullet for knowledge management and electronic commerce. Springer, Heidelberg

    MATH  Google Scholar 

  7. Pisanelli DM, ed (2004) Ontologies in medicine. IOS Press, Amsterdam

    Google Scholar 

  8. Gottgtroy P, Kasabov N, MacDonell S (2004) In: Zhang C, Guesgen HW, Yeap WK (eds) An ontology driven approach for knowledge discovery in Biomedicine. PRICAI 2004: Trends in Artificial Intelligence. Proc. VIII Pacific Rim Intl. Conf. AI, Lecture Notes in Artificial Intelligence, Vol. 3157. Springer-Verlag, Berlin

    Google Scholar 

  9. Gottgtroy P, Kasabov N, MacDonell S (2006) Evolving ontologies for intelligent decision support. In: Sanchez E (ed) Fuzzy Logic and the Semantic Web (Capturing Intelligence). Elsevier, Amsterdam

    Google Scholar 

  10. Gruber TR (1993) A translation approach to portable ontologies. Knowledge Acquisition 5:199–220

    Article  Google Scholar 

  11. Kasabov N, Benuskova L (2004) Computational neurogenetics. J. Comp. Theor. Nanoscience 1:47–61

    Article  Google Scholar 

  12. Kasabov N, Benuskova L, Wysoski SG (2005) Biologically plausible computational neurogenetic models: modeling the interaction between genes, neurons and neural networks. J. Comp. Theor. Nanoscience 2: 569–573

    Article  Google Scholar 

  13. Kasabov N, Jain V, Gottgtroy PCM, Benuskova L, Joseph F (2006) Brain gene ontology: integrating bioinformatics and neuroinformatics data, information and knowledge to enable discoveries. In: Abraham A, Kasabov N, Koeppen M, Koenig A, Song Q (eds) Proc. 6th Intl. Conf. Hybrid Intelligent Systems and 4th Conf. Neuro-Computing and Evolving Intelligence. IEEE, Auckland, New Zealand

    Google Scholar 

  14. Kasabov N, Jain V, Gottgtroy PCM, Benuskova L, Wysoski SG, Joseph F (2007) Evolving Brain-Gene Ontology System (EBGOS): towards Integrating Bioinformatics and Neuroinformatics Data to Facilitate Discoveries. International Joint Conference on Neural Networks, accepted.

    Google Scholar 

  15. Kasabov N (2003) Evolving connectionist systems. Methods and applications in bioinformatics, brain study and intelligent machines. Springer-Verlag, London

    Google Scholar 

  16. Pomeroy, S. L., P. Tamayo, Gaasenbeek M, Sturla LM, et al (2002) Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature 415:436–442

    Article  Google Scholar 

  17. Wysoski SG, Benuskova L, Kasabov N (2004) Simulation of neurogenetic models. In: Kasabov N, Chen ZSH (eds) Proc. 4th Conf. Neuro-Computing and Evolving Intelligence. AUT, Auckland, New Zealand

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Kasabov, N., Jain, V., Benuskova, L., Gottgtroy, P.C.M., Joseph, F. (2008). Integration of Brain-Gene Ontology and Simulation Systems for Learning, Modelling and Discovery. In: Kelemen, A., Abraham, A., Liang, Y. (eds) Computational Intelligence in Medical Informatics. Studies in Computational Intelligence, vol 85. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-75767-2_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-75767-2_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-75766-5

  • Online ISBN: 978-3-540-75767-2

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics