Abstract
To find the significant biomarker is very important in detecting protein patterns associated with diseases. In this study multilevel wavelet analysis is performed on high dimensional mass spectrometry data to extract the detail coefficients, which are used to detect the difference between cancer tissue and normal tissue. In order to find the key m/z values of mass spectra, wavelet detail information is reconstructed based on orthogonal wavelet detail coefficients, and genetic algorithm is further employed to select best features from the reconstructed detail information. Finally the corresponding significant m/z values of mass spectra are identified using the optimized detail features.
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References
Herrmann, P.C., Liotta, L.A., Petricoin, E.F.: Cancer Proteomics: The tate of the Art. Dis. Markers 17, 49–57 (2001)
Wright Jr., G.L., Cazares, L.H., Leung, S.M., Nasim, S., Adam, B.L., Yip, T.T., Schellhammer, P.F., Gong, L., Vlahou, A.: Protein Chip Surface Enhanced Laser Desorption/Ionization (SELDI) Mass Spectrometry: A Novel Protein Biochip Technology for Detection of Prostate Cancer Biomarkers in Complex Protein Mixtures. Prostate Cancer Prostatic Dis. 2, 264–276 (1999)
Vlahou, A., Schellhammer, P.F., Mendrinos, S., Patel, K., Kondylis, F.I., Gong, L., Nasim, S., Wright, J.: Development of a Novel Proteomic Approach for the Detection of Transitional Cell Carcinoma of the Bladder in Urine. Am. J. Pathol. 158, 1491–1520 (2001)
Lilien, R.H., Farid, H., Donald, B.R.: Probabilistic Disease Classification of Expression-Dependent Proteomic Data from Mass Spectrometry of Human Serum. Computational Biology 10 (2003)
Wu, B., Abbott, T., Fishman, D., McMurray, W., Mor, G., Stone, K., Ward, D., Williams, K., Zhao, H.: Comparison of Statistical Methods for Classification of Ovarian Cancer Using Mass Spectrometry Data. Bioinformatics 19 (2003)
Jeffries, N.O.: Performance of a Genetic Algorithm for Mass Spectrometry Proteomics. BMC Bioinformatics 5 (2004)
Levner, I.: Feature Selection and Nearest Centroid Classification for Protein Mass Spectrometry. BMC Bioinformatics 6 (2005)
Yu, J.S., Ongarello, S., Fiedler, R., Chen, X.W., Toffolo, G., Cobelli, C., Trajanoski, Z.: Ovarian Cancer Identification Based on dimensionality Reduction for High-throughput Mass Spectrometry Data. Bioinformatics 21, 2200–2209 (2005)
Liu, Y.: Feature Extraction for Mass Spectrometry Data. In: Li, K., Li, X., Irwin, G.W., He, G. (eds.) LSMS 2007. LNCS (LNBI), vol. 4689, pp. 188–196. Springer, Heidelberg (2007)
Liu, Y.: Cancer Classification Based on Mass Spectrometry. In: Masulli, F., Mitra, S., Pasi, G. (eds.) WILF 2007. LNCS (LNAI), vol. 4578, pp. 596–603. Springer, Heidelberg (2007)
Mallat, S.: A Theory for Multiresolution Signal Decomposition: The Wavelet Representation. IEEE Transactions on Pattern Analysis and Machine Intelligence 11, 674–693 (1989)
Daubechies, I.: Orthonormal Bases of Compactly Supported Wavelets. Communications on Pure and Applied Mathematics 41, 909–996 (1988)
Holland, J.H.: Adaptation in Natural and Artificial Systems. MIT Press, Cambridge (1992)
Blanco, M., Delgado, M.C.: Pegalajar: A Real-coded Genetic Algorithm for Training Recurrent Neural Networks. Neural Networks 14, 93–105 (2001)
Herrera, F., Lozano, M., Verdegay, J.L.: Tackling Real-coded Genetic Algorithms: Operators and Tools for Behavioral Analysis. Artif. Intell. Rev. 12, 265–319 (1998)
Petricoin, E.F., Ornstein, D.K., Paweletz, C.P., Ardekani, A., Hackett, P.S., Hitt, B.A., Velassco, A., Trucco, C., Wiegand, L., Wood, K., Simone, C.B., Levine, P.J., Linehan, W.M., Emmert-Buck, M.R., Steinberg, S.M., Kohn, E.C., Liotta, L.A.: Serum Proteomic Patterns for Detection of Prostate Cancer. J. Natl. Cancer Inst. 94, 1576–1578 (2002)
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Liu, Y., Bai, L. (2008). Find Key m/z Values in Predication of Mass Spectrometry Cancer Data. In: Huang, DS., Wunsch, D.C., Levine, D.S., Jo, KH. (eds) Advanced Intelligent Computing Theories and Applications. With Aspects of Theoretical and Methodological Issues. ICIC 2008. Lecture Notes in Computer Science, vol 5226. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-87442-3_25
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DOI: https://doi.org/10.1007/978-3-540-87442-3_25
Publisher Name: Springer, Berlin, Heidelberg
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