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Finding Correlation between Protein Protein Interaction Modules Using Semantic Web Techniques

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Advances in Computer Science and Engineering (CSICC 2008)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 6))

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Abstract

Many complex networks such as social networks and computer show modular structures, where edges between nodes are much denser within modules than between modules. It is strongly believed that cellular networks are also modular, reflecting the relative independence and coherence of different functional units in a cell. In this paper we used a human curated dataset. In this paper we consider each module in the PPI network as ontology. Using techniques in ontology alignment, we compare each pair of modules in the network. We want to see that is there a correlation between the structure of each module or they have totally different structures. Our results show that there is no correlation between proteins in a protein protein interaction network.

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Author information

Authors and Affiliations

  1. Department of Computer Engineering, Sharif University of Technology, Tehran, Iran

    Mehdi Kargar, Shahrouz Moaven & Hassan Abolhassani

Authors
  1. Mehdi Kargar
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  2. Shahrouz Moaven
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  3. Hassan Abolhassani
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Editor information

Editors and Affiliations

  1. IPM School of Computer Science, and Department of Computer Engineering, Sharif Unversity of Technology, Azadi Street, Tehran, Iran

    Hamid Sarbazi-Azad

  2. Department of Electrical and computer Engineering, UC Irvine, California, USA

    Behrooz Parhami

  3. Department of Computer Engineering, Sharif University of Technology,, Azadi Street, Tehran, Iran

    Seyed-Ghassem Miremadi

  4. Department of Computer Engineering, Sharif University of Technology, Azadi Street, Tehran, Iran

    Shaahin Hessabi

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© 2008 Springer-Verlag Berlin Heidelberg

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Kargar, M., Moaven, S., Abolhassani, H. (2008). Finding Correlation between Protein Protein Interaction Modules Using Semantic Web Techniques. In: Sarbazi-Azad, H., Parhami, B., Miremadi, SG., Hessabi, S. (eds) Advances in Computer Science and Engineering. CSICC 2008. Communications in Computer and Information Science, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-89985-3_154

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  • DOI: https://doi.org/10.1007/978-3-540-89985-3_154

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-89984-6

  • Online ISBN: 978-3-540-89985-3

  • eBook Packages: Computer ScienceComputer Science (R0)

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