Abstract
One important information for the classification of epilepsy is the spatial localization of the discharges source. Juvenile myoclonic epilepsy (JME) is an idiopathic generalized epilepsy (IGE) that typically presents generalized tonic-clonic, myoclonic, or absence seizures, or a combination of these. In typical cases of JME, the seizures are usually bilateral and symmetric, and EEG shows generalized interictal epileptiform discharges and a generalized seizure pattern that also is bilaterally synchronous. Despite of the generalized pattern of this type of epilepsy, there are some electroencephalographic and clinical features that suggest a frontal origin for the discharges. In this work, EEG recordings were analyzed in order to find evidences for this frontal origin in JME. The analysis of the signals was based on independent component analysis (ICA) for separating epileptiform discharges from artifacts and other brain sources; then the discharge components were used to spatially localize its source. In the six patients the dipole sources were localized mainly in the frontal region, what suggests an important participation of the frontal lobe for this kind of epilepsy.
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Gomes, S.P., da Silva Sousa-Carvalho, P., Aguiar, E., Silva, A.B., Braga, F.M., Barros, A.K. (2009). Localization of Generalized Discharge Sources in Patients with Juvenile Myoclonic Epilepsy Using Independent Components Analysis. In: Adali, T., Jutten, C., Romano, J.M.T., Barros, A.K. (eds) Independent Component Analysis and Signal Separation. ICA 2009. Lecture Notes in Computer Science, vol 5441. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-00599-2_52
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DOI: https://doi.org/10.1007/978-3-642-00599-2_52
Publisher Name: Springer, Berlin, Heidelberg
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