Abstract
In this study, the plastic change in the auditory cortex induced by fear conditioning with pairing of sound (Conditioned Stimulus, CS) and electric foot-shock (Unconditioned Stimulus, US) was investigated by using of an optical recording. To investigate the effect of associated learning, optical signals in the auditory cortex to CS (12 kHz pure tone) and non-CS (8 kHz and 16 kHz pure tone) were recorded before and after the conditioning. As a result, the response area only to CS increased after the conditioning. On the other hand, to investigate whether auditory information could be retrieved by electric foot-shock after associated learning or not, auditory response to foot-shock alone was also investigated. As a result, the optical response in the auditory cortex to electric foot-shock alone could not be observed before the conditioning but clearly appeared after the conditioning.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bakin, J.S., Weinberger, N.M.: Classical conditioning induces CS-specific receptive field plasticity in the auditory cortex of the guinea pig. Brain Res. 536, 271–286 (1990)
Recanzone, G.H., Schreiner, C.E., Merzenich, M.M.: Plasticity in the frequency representation of primary auditory cortex following discrimination training in adult owl monkeys. J. Neurosci. 13, 87–103 (1993)
Horikawa, J., Hosokawa, Y., Kubota, M., Nasu, M., Taniguchi, I.: Optical imaging of spatiotemporal patterns of glutamatergic excitation and GABAergic inhibition in the guinea-pig. J. Physiol. 497, 629–638 (1996)
Kilgard, M.P., Merzenich, M.M.: Cortical map reorganization enabled by nucleus basalis activity. Science 279, 1714–1718 (1998)
Bandrowski, A.E., Moore, S.L., Ashe, J.H.: Cholinergic synaptic potentials in the supragranular layers of auditory cortex. Synapse 41, 118–130 (2001)
Weinberger, N.M., Bakin, J.S.: Learning induced physiological memory in adult primary auditory cortex: Receptive field plasticity, model, and mechanisms. Audiology & Neuro-Otology 3, 145–167 (1998)
Bakin, J.S., Weinberger, N.M.: Induction of a physiological memory in the cerebral cortex by stimulation of the nucleus basalis. Proc. Natl. Acad. Sci. U S A 93, 11219–11224 (1996)
Herrero, J.L., Roberts, M.J., Delicato, L.S., Giesemann, M.A., Dayan, P., Thiele, A.: Acetylecholine contributes through muscarinic receptors to attentional modulation in V1. Nature 454, 1110–1114 (2008)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2009 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Ide, Y., Lauwereyns, J., Tsukada, M. (2009). Optical Imaging of Plastic Changes Induced by Fear Conditioning in the Auditory Cortex of Guinea Pig. In: Köppen, M., Kasabov, N., Coghill, G. (eds) Advances in Neuro-Information Processing. ICONIP 2008. Lecture Notes in Computer Science, vol 5506. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02490-0_51
Download citation
DOI: https://doi.org/10.1007/978-3-642-02490-0_51
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-02489-4
Online ISBN: 978-3-642-02490-0
eBook Packages: Computer ScienceComputer Science (R0)