Skip to main content

Retinal Vessel Extraction by a Combined Neural Network–Wavelet Enhancement Method

  • Conference paper

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 5755))

Abstract

This paper presents a combined approach to automatic extraction of blood vessels in retinal images. The proposed procedure is composed of two phases: a wavelet transform-based preprocessing phase and a NN-based one. Several neural net topologies and training algorithms are considered with the aim of selecting an effective combined method. Human retinal fundus images, derived from the publicly available ophthalmic database DRIVE, are processed to detect retinal vessels. The approach is tested by considering performances in terms of sensitivity and specificity values obtained from vessel classification. The quality of vessel identifications is evaluated on obtained image by computing both sensitivity values and specificity ones and by relating them in ROC curves. A comparison of performances by ROC curve areas for various methods is reported.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Pattona, N., Aslamc, T.M., Mac, G.T., Dearye, I.J., Dhillonb, B., Eikelboomf, R.H., Yogesana, G.K., Constablea, I.J.: Retinal image analysis: Concepts, applications and potentials. Progress in Retinal and Eye Research 25, 99–127 (2006)

    Article  Google Scholar 

  2. Kanski, J.J.: Clinical Opthalmology, 3rd edn. Butterworth Heinemann, Butterworths (1997)

    Google Scholar 

  3. Kirbas, C., Quek, F.K.H.: Vessel extraction techniques and algorithms: a survey. In: Third IEEE Sym. on Bioinformatics & Bioengineering, Bethesda, Maryland, March 10-12, pp. 238–245 (2003)

    Google Scholar 

  4. Carnimeo, L.: Diabetic Damage Detection in Retinal Images via a Sparsely-Connected Neurofuzzy Network. In: Huang, D.-S., Wunsch II, D.C., Levine, D.S., Jo, K.-H. (eds.) ICIC 2008. LNCS (LNAI), vol. 5227, pp. 1175–1182. Springer, Heidelberg (2008)

    Chapter  Google Scholar 

  5. Li, H., Hsu, W., Lee, M.L., Wang, H.: Automatic grading of retinal vessel calibre. IEEE Trans on Biomedical Engineering 52(7), 1352–1355 (2005)

    Article  Google Scholar 

  6. Jiang, X., Mojon, D.: Adaptive local thresholding by verification-based multithreshold probing with application to vessel detection in retinal images. IEEE Trans. on Pattern Analysis & Machine Intelligence 25(1), 131–137 (2003)

    Article  Google Scholar 

  7. Antoine, J., Carette, P., Murenzi, R., Piette, B.: Image analysis with two-dimensional continuous wavelet transform. Signal Processing 31(3), 241–272 (1993)

    Article  MATH  Google Scholar 

  8. Soares, J.V.B., Leandro, J.J.G., Cesar-Jr, R.M., Jelinek, H.F., Cree, M.J.: Retinal vessel segmentation using the 2-d gabor wavelet and supervised classification. IEEE Trans. on Medical Imaging 25(9), 1214–1222 (2006)

    Article  Google Scholar 

  9. Cornforth, D.J., Jelinek, H.J., Leandro, J.J.G., Soares, J.V.B., Cesar-Jr, R.M., Cree, M.J., Mitchell, P., Bossomaier, T.: Development of retinal blood vessel segmentation methodology using wavelet transforms assesment of diabetic retinopathy. In: Proc. of 8th Asia Pacific Sym. on Intelligent & Evolutionary Systems, Cairns, Australia, December 6-7, pp. 50–60 (2004)

    Google Scholar 

  10. Zana, F., Klein, J.C.: Segmentation of vessel-like patterns using mathematical morphology and curvature evaluation. IEEE Trans. on Image Processing 10(7), 1010–1019 (2001)

    Article  MATH  Google Scholar 

  11. Frangi, A.F., Niessen, W.J., Vincken, K.L., Viergever, M.: Multiscale vessel enhancement filtering. In: Proc. of the 1st Int. Conf. on Medical Image Computing & Computer-Assisted Intervention, Cambrige MA, USA, October 11-13, pp. 130–137 (1998)

    Google Scholar 

  12. Sofka, M., Stewart, C.V.: Retinal vessel extraction using multiscale matched filters, confidence and edge measures. IEEE Trans. on Medical Imaging 25(12), 1531–1546 (2006)

    Article  Google Scholar 

  13. Staal, J., Abramoff, M.D., Niemeijer, M., Viergever, M.A., van Ginneken, B.: Ridge based vessel segmentation in colour images of the retina. IEEE Trans. on Medical Imaging 23, 501–509 (2004)

    Article  Google Scholar 

  14. Staal, J., Kalitzin, S.N., Viergever, M.A.: A trained spin-glass model for grouping of image primitives. IEEE Trans. on Pattern Analysis and Machine Intelligence 27(7), 1172–1182 (2005)

    Article  Google Scholar 

  15. Vermeer, V., Lemij, V.: A model based method for retinal blood vessel detection. Computers in Biology and Medicine 34(3), 209–219 (2004)

    Article  Google Scholar 

  16. Niemeijer, M., Staal, J., van, G.B., Loog, M., Abramoff, M.D.: Comparative study of retinal vessel segmentation methods on a new publicly available database. In: SPIE Medical Imaging, San Diego, CA, USA, February 14, pp. 648–656 (2004)

    Google Scholar 

  17. Heneghan, F., O’Keefe, C.: Characterization of changes in blood vessel width and tortuosity in retinopathy of prematurity using image analysis. Medical Image Analysis 6(4), 407–429 (2002)

    Article  Google Scholar 

  18. Fawcett, T.: An introduction to ROC analysis. Pattern Recognition Letters 27(8), 861–874 (2006)

    Article  MathSciNet  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Carnimeo, L., Bevilacqua, V., Cariello, L., Mastronardi, G. (2009). Retinal Vessel Extraction by a Combined Neural Network–Wavelet Enhancement Method. In: Huang, DS., Jo, KH., Lee, HH., Kang, HJ., Bevilacqua, V. (eds) Emerging Intelligent Computing Technology and Applications. With Aspects of Artificial Intelligence. ICIC 2009. Lecture Notes in Computer Science(), vol 5755. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-04020-7_118

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-04020-7_118

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-04019-1

  • Online ISBN: 978-3-642-04020-7

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics